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MetabolomicsQuantitative LC-MS study of compounds found predictive of COVID-19 severity and outcome

INTRODUCTION: Since the beginning of the SARS-CoV-2 pandemic in December 2019 multiple metabolomics studies have proposed predictive biomarkers of infection severity and outcome. Whilst some trends have emerged, the findings remain intangible and uninformative when it comes to n...

2024-04-23 | MTBLS7429 | MetaboLights
MetabolomicsMaternal Gut Microbiota Influences Immune Activation at the Maternal-Fetal Interface Affecting Pregnancy Outcome

Preeclampsia is a leading cause of morbidity and mortality in pregnant women, affecting 5-8% of gestations worldwide. Its development is influenced by maternal immune abnormalities, metabolic disorders and gut dysbiosis. In this study, we show that gut dysbiosis in pregnant C57BL/6J dams leads to...

2025-05-07 | MTBLS12316 | MetaboLights
MetabolomicsUntargeted urine LC-HRMS metabolomics profiling for bladder cancer binary outcome classification
Not available
ORGANISM(S): Homo sapiens 
ST001682 | MetabolomicsWorkbench
MetabolomicsmTOR regulates metabolic adaptation of APCs in the lung microenvironment and controls the outcome of allergic inflammation
Not available
ORGANISM(S): Mus musculus 
ST000657 | MetabolomicsWorkbench
TranscriptomicsA gene expression profile of BRCAness that is associated with outcome in ovarian cancer
A gene expression profile of BRCAness was defined in publicly available expression data of 61 patients with epithelial ovarian cancer (34 patients with BRCA-1 or BRCA-2 mutations and 27 patients with sporadic disease). This dataset is publicly available at http://jnci.oxfordjournals.org/cgi/content/...
ORGANISM(S): Homo sapiens 
2010-07-11 | E-GEOD-19829 | biostudies-arrayexpress
Proteomicsfunctional biomarker which could be used to predict connective healing based on an Achilles Tendon Model
Healing process after connective tissues (CT) injury is complex but important as CT are critical for human moving, and patient outcome of CT injured patients is protracted with high individual variation. Specific markers which could be used for healing prognosis will be great help to monitor patient...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD033163 | Pride
Ms Connective tissue Healing Fibroblast Eef2 Biomarker 
TranscriptomicsThe gene expression signature of genomic instability in breast cancer is an independent predictor of clinical outcome
Recently, expression profiling of breast carcinomas has revealed gene signatures that predict clinical outcome, and discerned prognostically relevant breast cancer subtypes. Measurement of the degree of genomic instability provides a very similar stratification of prognostic groups. We therefore...
ORGANISM(S): Homo sapiens 
2009-11-30 | E-GEOD-11901 | biostudies-arrayexpress
ProteomicsUsing Quantitative Proteomic Assessments and their Association with Long Term Healing Outcomes
Healing after Achilles tendon rupture (ATR) is protracted with high individual variation and unsatisfactory outcome. Biomarkers prognostic of healing are unknown while physical and mechanical factors are used for predicting long-term healing outcomes in clinics today. The present study was designed ...
ORGANISM(S): Homo sapiens (Human) 
2022-05-25 | PXD029202 | Pride
Outcome Proteomics Mass spectrometry Healing Achilles tendon rupture Biomarkers 
TranscriptomicsA Genomic Score Prognostic of Outcome in Trauma Patients
Physiological, anatomical, and clinical laboratory analytic scoring systems (APACHE, Injury Severity Score (ISS)) have been utilized, with limited success, to predict outcome following injury. We hypothesized that a peripheral blood leukocyte gene expression score could predict outcome, including mu...
ORGANISM(S): Homo sapiens 
2009-04-12 | E-GEOD-11375 | biostudies-arrayexpress
TranscriptomicsPeripheral Blood Mononuclear Cell Gene Expression Profiles May Predict Poor Outcome in Idiopathic Pulmonary Fibrosis [Affymetrix]
Background: In this study we aimed to identify peripheral blood mononuclear cell (PBMC) gene expression profiles predictive of poor outcomes in idiopathic pulmonary fibrosis (IPF) Methods: Microarray analyses of PBMC were performed in 120 patients from discovery (n=45) and replication cohorts (n=7...
ORGANISM(S): Homo sapiens 
2013-10-15 | E-GEOD-27957 | biostudies-arrayexpress
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