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OtherThe Shotgun Proteomic Study of the Human ThinPrep Cervical Smear Using iTRAQ Mass-Tagging and 2D LC-FT-Orbitrap-MS: The Detection of the Human Papillomavirus at the Protein Level.
Data from ProteomeXchante, PXD ID: PXD000109. Data file: 29SEP12_cervical_smear_1st_exp_HCD.msf.mgf. Published as part of J Proteome Res. 2013 May 3;12(5):2078-89 . From the Abstract: {{i}}{{/i}} ... In this study, an LC-MS method based on isobaric (iTRAQ) labeling and high-resolution FT-Orbitrap m...
ORGANISM(S): Human, Escherichia_coli_k_12_substr__dh10b, Human_adenovirus_54, Human_adenovirus_a, Human_adenovirus_b, Human_adenovirus_c, Human_adenovirus_d, Human_adenovirus_e, Human_adenovirus_f, Human_adenovirus_g, Human_astrovirus, Human_bocavirus, Human_bocavirus_2, Human_bocavirus_3, Human_bocavirus_4, Human_coronavirus_229e, Human_coronavirus_hku1, Human_coronavirus_nl63, Human_coronavirus_oc43, Human_cosavirus_a, Human_cosavirus_b, Human_cosavirus_d, Human_cosavirus_e, Human_enteric_coronavirus_4408, Human_enterovirus_100, Human_enterovirus_a, Human_enterovirus_b, Human_enterovirus_c, Human_enterovirus_d, Human_erythrovirus_v9, Human_herpesvirus_1, Human_herpesvirus_2, Human_herpesvirus_3, Human_herpesvirus_4_type_1, Human_herpesvirus_4_type_2, Human_herpesvirus_5, Human_herpesvirus_6a, Human_herpesvirus_6b, Human_herpesvirus_7, Human_herpesvirus_8_type_p, Human_immunodeficiency_virus_1, Human_immunodeficiency_virus_2, Human_metapneumovirus, Human_papillomavirus_fa75_ki88_03, Human_papillomavirus_rtrx7, Human_papillomavirus_type_10, Human_papillomavirus_type_100, Human_papillomavirus_type_101, Human_papillomavirus_type_103, Human_papillomavirus_type_104, Human_papillomavirus_type_105, Human_papillomavirus_type_108, Human_papillomavirus_type_109, Human_papillomavirus_type_112, Human_papillomavirus_type_113, Human_papillomavirus_type_16, Human_papillomavirus_type_24, Human_papillomavirus_type_26, Human_papillomavirus_type_32, Human_papillomavirus_type_34, Human_papillomavirus_type_4, Human_papillomavirus_type_41, Human_papillomavirus_type_48, Human_papillomavirus_type_49, Human_papillomavirus_type_5, Human_papillomavirus_type_50, Human_papillomavirus_type_53, Human_papillomavirus_type_60, Human_papillomavirus_type_63, Human_papillomavirus_type_6b, Human_papillomavirus_type_7, Human_papillomavirus_type_71, Human_papillomavirus_type_88, Human_papillomavirus_type_9, Human_papillomavirus_type_92, Human_papillomavirus_type_96, Human_papillomavirus_type_98, Human_papillomavirus_type_99, Human_papillomavirus___1, Human_papillomavirus___18, Human_papillomavirus___2, Human_papillomavirus___54, Human_papillomavirus___61, Human_papillomavirus___cand90, Human_parainfluenza_virus_1, Human_parainfluenza_virus_2, Human_parainfluenza_virus_3, Human_parechovirus, Human_parvovirus_4, Human_parvovirus_b19, Human_picobirnavirus, Human_respiratory_syncytial_virus, Human_rhinovirus_a, Human_rhinovirus_b, Human_rhinovirus_c, Human_tmev_like_cardiovirus, Human_t_lymphotropic_virus_1, Human_t_lymphotropic_virus_2, Human_t_lymphotropic_virus_4 
GPM11210017082 | GPMDB
Resource Reanalysis 
ProteomicsCRISPR-Cas9 genetic screen leads to the discovery of L-Moses, a KAT2B inhibitor that attenuates Tunicamycin-mediated neurodegeneration
Accumulation of aggregated and misfolded proteins, leading to endoplasmic reticulum stress and activation of the unfolded protein response, is a hallmark of several neurodegenerative disorders, including Alzheimer’s and Parkinson’s disease. Genetic screens are powerful tools that are proving invalua...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD038395 | Pride
Cortical neurons Kat2b L-moses Endoplasmic reticulum (er) stress Acetylome 
ProteomicsA quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes
Understanding the dynamics of endogenous protein-protein interactions in complex networks is pivotal in deciphering the mechanisms underlying diseases such as cancer. To enable the in-depth analysis of protein interactions in chromatin-associated protein complexes, we have previously developed a met...
ORGANISM(S): Homo sapiens (Human) 
2018-06-08 | PXD007968 | Pride
Breast cancer Proteomics Qplex-rime Tmt 4-hydrotamoxifen Rime Clinical samples Isobaric labelling Patient derived xenografts (pdx) Estrogen receptor alpha Interactome 
ProteomicsThinPrep Cervical Smear iTRAQ LC-MS/MS
The protein content from ThinPrep cervical smear specimens was purified with TCA precipitation. The protein pellets were dissolved and protein concentration was measured with the Bradford assay. 100 ug of protein for each sample were reduced with TCEP, cysteines were blocked with MMTS and finally d...
ORGANISM(S): Homo sapiens (Human) 
2013-05-09 | PXD000109 | Pride
Hpv Orbitrap elite Thinprep Itraq 
UnknownCRISPR-Cas9 genetic screen leads to the discovery of L-Moses, a KAT2B inhibitor that attenuates Tunicamycin-mediated neuronal cell death.
Not available
S-EPMC9998435 | biostudies-literature
ProteomicsARID1A RIME in human cell lines and tissue xenografts.
Examination of chromatin-bound proteins associated with ARID1A, BRG1 and ERa in MCF7 cells and ERa in ER+ patient-derived xenografts using RIME protocol and mass spectrometry.
ORGANISM(S): Homo sapiens (Human) 
2019-10-31 | PXD011810 | Pride
Human Arid1a Rime Qplex 
UnknownA quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes.
Not available
S-EPMC5998130 | biostudies-literature
UnknownARID1A influences HDAC1/BRD4 activity, intrinsic proliferative capacity and breast cancer treatment response.
Not available
S-EPMC7116647 | biostudies-literature
UnknownTandem Duplications in UBTF Create XPO1-Dependent Nuclear Export Signals that Reveal a Leukemic Therapeutic Dependency.
Not available
S-EPMC12793833 | biostudies-literature
UnknownIndomethacin with or without prophylactic pancreatic stent placement to prevent pancreatitis after ERCP: a randomised non-inferiority trial.
Not available
S-EPMC10872215 | biostudies-literature
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