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ProteomicsHLA-I peptidomes and phosphopeptidomes (B*40, B*27, B*07, B*39)
As aberrant phosphorylation is a hallmark of tumor cells, the display of tumor-specific phosphopeptides by Human Leukocyte Antigen (HLA) class I molecules can be exploited in the treatment of cancer by T-cell-based immunotherapy. Yet, the characterization and prediction of HLA-I phospholigands is ch...
ORGANISM(S): Homo sapiens (Human) 
2016-12-12 | PXD005084 | Pride
Phosphopeptidome Mhc Peptidome Hla 
ProteomicsProteomics profiling of vitreous humor reveals complement and coagulation components, adhesion factors, and neurodegeneration markers as discriminatory biomarkers of vitreoretinal eye diseases
Diabetic retinopathy (DR) and age-related macular degeneration (AMD) are leading causes of visual impairment and blindness in people aged 50 years or older in middle-income and industrialized countries. Anti-VEGF therapies have improved the management of neovascular AMD (nAMD) and proliferative DR (...
ORGANISM(S): Homo sapiens (Human) 
2023-03-09 | PXD038285 | Pride
Complement and coagulation cascades Age-related macular degeneration Neurodegeneration Vitreous proteomics. Extracellular matrix Proliferative diabetic retinopathy Biomarkers Retinal detachment 
ProteomicsMHC Peptidomics: HLA-B*27 vs Mamu-B*08
Indian rhesus macaques are arguably the most reliable animal models in AIDS research. In this species the MHC class I allele Mamu-B*08, among others, is associated with elite control of SIV replication. A similar scenario is observed in humans where the expression of HLA-B*27 or HLA-B*57 has been li...
ORGANISM(S): Homo sapiens (Human) 
2016-10-07 | PXD004964 | Pride
Peptides Hla-b*27 Mhc Hiv Peptidomics Mamu-b*08 Lc-ms/ms Siv 
ProteomicsProteomic analysis of the human milieu of gamete /embryo maternal interaction
The improvement of the embryo culture media is of high relevance due to its influence on successful implantation rates, pregnancy, neonatal outcomes and potential effects in the adult life. The ideal conditions for embryo development are those naturally occurring in the female reproductive tract, i....
ORGANISM(S): Homo sapiens (Human) 
2019-10-29 | PXD015980 | Pride
Low abundance proteins  human reproductive fluids  salpingectomy 
ProteomicsCNB Lipid Rafts reAnalysis. - This dataset represents an example for a textbook: Genomics and Proteomics for Clinical Discovery and Development
This dataset represents an example for a textbook: Genomics and Proteomics for Clinical Discovery and Development, http://www.springer.com/life+sciences/systems+biology+and+bioinformatics/book/978-94-017-9201-1 ReAnalysis of the work Proteomic analysis of apical microvillous membranes of syncytio...
ORGANISM(S): Homo sapiens (Human) 
2014-07-14 | PXD000744 | Pride
Protein annotations Reanalysis Lipid rafts 
ProteomicsETFDH, CIII and COQ2 common interactome
Proteomic analysis of the immunocapture (IP) of COQ2, ETFDH and UQCRC2 in skeletal muscle extracts, searching for common interactors Coenzyme Q (Q) is a key lipid electron transporter, but several aspects of its biosynthesis and redox homeostasis remain undefined. Various flavoproteins reduce the Q;...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-24 | PXD045351 | Pride
Etfdh  coenzyme q  oxphos-complex iii  skeletal muscle 
ProteomicsETFDH comigrates with CIII in BN-PAGE
Proteomic analysis of 13 bands from BN-PAGE immunostaining of mouse skeletal muscle mitochondrial proteins: Coenzyme Q (Q) is a key lipid electron transporter, but several aspects of its biosynthesis and redox homeostasis remain undefined. Various flavoproteins reduce the Q; however, in eukaryotes, ...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-24 | PXD045352 | Pride
Coenzyme q  oxphos-complex iii  skeletal muscle  mitochondria 
ProteomicsABRFsprg2010 CNB - The ProteoRed MIAPE web toolkit: a user-friendly framework to connect and share proteomics standards
Not available
2012-05-02 | PRD000381 | Pride
ProteomicsTwo elongasomes generate rod shape in a unicellular microorganism
Cell geometry is genetically inherited by all forms of life. In bacteria, shape is determined by the peptidoglycan and is nearly invariant during the metabolically active vegetative state. Essential morphogenetic complexes, the elongasome and divisome, expand the peptidoglycan along the major and mi...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344 
2023-08-15 | PXD039436 | Pride
Salmonella  peptidoglycan  elongasome  pbp2  pbp2sal 
ProteomicsA proteomics approach to study the role of lipid droplets in plant defense
Lipid Droplets (LDs), classically viewed as lipid storage particles, are recently emerging as dynamic organelles associated with stress responses and development; however, their involvement in plant immunity has been little investigated. Here we studied LDs in Arabidopsis thaliana leaves that respon...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2022-02-23 | PXD011499 | Pride
Lipid droplets/pseudomonas/hr-induced defense/senescence/arabidopsis 
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