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Autism Spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder where patients have impaired social behavior and communication, and restricted interests. Although various studies have been carried out to unveil the mechanisms associated with ASD, its pathophysiology is still poorly und...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD031656 | Pride
Xanthomonas oryzae pv. oryzae (Xoo) is a rice pathogen causing bacterial blight, which outbreaks in most rice cultivating countries and reduces yield up to 50% due to no effective pesticide. Urgent responses of Xoo upon the initial contacts with rice at infection site are essential for pathogenesis....
ORGANISM(S): Xanthomonas oryzae pv. oryzae KACC 10331 
2021-09-09 | PXD020135 | Pride
Niclosamide has emerged as a promising drug for cardiac valve calcification treatment. Previous study suggested niclosamide's protective effects against vascular smooth muscle cell calcification. Yet, its impact on human VICs remained unexplored. In this study, we performed global and phospho-proteo...
ORGANISM(S): Homo sapiens (Human) 
2026-10-15 | PXD047708 | Pride
We determined the genomic locations of the SigR binding sites by chromatin immuno-precipitation of cross-linked DNA and hybridization on a tilling oligonucleotide array after 20 minutes of diamide treatment on cell cultures. Three independent biological samples were prepared separately from the wild...
ORGANISM(S): Streptomyces coelicolor A3(2) 
Lists of proteins that were commonly detected in total, membrane, TMP, and vesicles.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2018-08-15 | MSV000082822 | MassIVE
SNP 6.0 arrays of small cell lung cancer
Whole genome sequencing was performed with DNA extracted from fresh-frozen tumor and normal material. Short insert DNA libraries were prepared with the TruSeq DNA PCRfree sample preparation kit (Illumina) for paired-end sequencing at a minimum read length of 2x100bp. Human DNA libraries were sequenc...
RNA-sequencing (RNA-seq) was performed with RNA extracted from fresh-frozen human tumor tissue samples. cDNA libraries were prepared from poly-A selected RNA applying the Illumina TruSeq protocol for mRNA. The libraries were then sequenced with a 2 x 100bp paired-end protocol to a minimum mean cover...
We have sequenced the genomes of 110 small cell lung cancers (SCLC), one of the deadliest human cancers. We found bi-allelic inactivation of TP53 and RB1 in nearly all the tumors analyzed, sometimes by complex genomic rearrangements. Two tumors with wild-type RB1 had evidence of chromothripsis leadi...
Data Access Committee EGAC00001000064
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