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Legumain is a cysteine protease broadly associated with inflammation. It has recently been reported to cleave and activate protease-activated receptor 2 to provoke pain associated with oral cancer. Outside of gastric and colon cancer, little has been reported on the roles of legumain within the gast...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-29 | PXD051470 | Pride
The mammalian lysosomal protease legumain is often dysregulated in pathophysiological conditions including inflammation, neurodegeneration, and cancer, yet its proteolytic targets are poorly defined. To profile protease substrates degradomics techniques typically employ enrichment strategies to sele...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-29 | PXD060852 | Pride
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