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UnknownTreatment of Patients With Metastatic Cancer Using a Major Histocompatibility Complex Class II-Restricted T-Cell Receptor Targeting the Cancer Germline Antigen MAGE-A3.
Not available
S-EPMC5652397 | biostudies-literature
TranscriptomicsSynovial biopsies from RA and PsA patients and skin biopsies from Psoriasis patients under Infliximab treatment
Object: to understand Infliximab treatment effect on the molecular expression of tissue at disease site 4mm punch biopsies were performed on involved and uninvolved skin at baseline in 5 Ps patients. A repeat biopsy was performed at week 2 after IFX therapy at a site adjacent to the baseline biopsy ...
ORGANISM(S): Homo sapiens 
2014-10-29 | E-GEOD-57376 | biostudies-arrayexpress
UnknownPopulation genetic structure of Phaedranassa cinerea Ravenna (Amaryllidaceae) and conservation implications.
Not available
S-EPMC11760094 | biostudies-literature
ProteomicsTargeted Protein Acetylation in Cells Using Heterobifunctional Molecules
Protein acetylation is a central event in orchestrating diverse cellular processes. However, current strategies to investigate protein acetylation in cells are often non-specific or lack temporal and magnitude control. Here, we developed an acetylation tagging system, AceTAG, to induce acetylation o...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD027617 | Pride
Targeted acetylation Acetylproteomics P300/cbp Heterobifunctional molecules 
ProteomicsHuman Milk Oligosaccharide Interactions in Mouse Macrophage
Chemoproteomic profiling of Human Milk Oligosaccharide Interactions in Mouse Macrophages
ORGANISM(S): Mus musculus (Mouse) 
2022-10-13 | PXD035729 | Pride
Macrophage Raw264.7 Human milk oligosaccharide Chemoproteomics Diazirine Mouse 
ProteomicsPortimine profiling in Human and mouse cells
practipractical access to the portimines and analogs thereof simplified the development of photoaffinity analogs, which were used in chemical proteomic experiments to identify a primary target of portimine A as the 60S ribosomal export protein NMD3cal access to the portimines and analogs thereof sim...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2023-07-12 | PXD041911 | Pride
Human mouse 
ProteomicsChemoproteomics-guided development of SLC15A4 inhibitors with anti-inflammatory activity
SLC15A4 is an endolysosome-resident transporter intimately linked with autoinflammation and autoimmunity. Specifically, SLC15A4 is critical for Toll-like receptor (TLR) 7-9 as well as the nucleotide-binding oligomerization domain-containing protein (NOD) signaling in several immune cell subsets. Not...
ORGANISM(S): Homo sapiens (Human) 
2023-11-29 | PXD045715 | Pride
Chemoproteomic Anti-inflammatory Slc15a4 
UnknownAdding Celecoxib With or Without Zoledronic Acid for Hormone-Naive Prostate Cancer: Long-Term Survival Results From an Adaptive, Multiarm, Multistage, Platform, Randomized Controlled Trial.
Not available
S-EPMC5455701 | biostudies-literature
TranscriptomicsTranscription profiling of human stage 1,2 normal and tumor kidney cancer
Although renal cell carcinoma (RCC) is the sixth-leading cause of cancer death, the molecular events leading to disease onset and progression are not well understood. Genomic profiling of clear cell RCC (cRCC) patients indicated that loss of a negative regulator of the Wnt pathway, secreted frizzled...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-6344 | biostudies-arrayexpress
ProteomicsGel LC-MS/MS analyses of MMP cleavage of tryptophanyl-tRNA synthetase
Tryptophanyl-tRNA synthetase was incubated by MMPs, cleavage products were resolved on SDS-PAGE. Cleavage products were trypsin digested and analyzed by LC-MS/MS.
ORGANISM(S): Homo sapiens (Human) 
2019-05-29 | PXD013217 | Pride
Mmp Protease Lc-ms/ms 
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