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The species Campylobacter jejuni is naturally competent for DNA uptake; nevertheless, nonnaturally transformable strains do exist. For a subset of strains we previously showed that a periplasmic DNase, encoded by dns, inhibits natural transformation in C. jejuni. In the present study, genetic factor...
ORGANISM(S): Campylobacter jejuni 
Respiratory syncytial virus inhibits Type I Interferon signaling to maintain HLA-DM expression in CD1c + Dendritic cells
Identifying cis-regulatory elements is important to understand how human pancreatic islets modulate gene expression in physiologic or pathophysiologic (e.g., diabetic) conditions. We conducted genome-wide analysis of DNase I hypersensitive sites, histone H3 lysine methylation marks (K4me1, K4me3, K7...
ORGANISM(S): Homo sapiens 
We present data from tissues of seven oesophageal adenocarcinomas of CD4 and CD8 T cell epitopes eluted from the cell surface using mass spectrometry (immunopeptidomics) of presented HLA bound peptides.This dataset forms part of the publication:Nicholas, B., Bailey, A., McCann, K.J., Wood, O., Walke...
ORGANISM(S): Homo sapiens (Human) 
2022-09-27 | PXD031108 | Pride
Mitochondria are the major source of cellular energy (ATP), as well as critical mediators of widespread functions such as cellular redox balance, apoptosis, and metabolic flux. Methods to quantify mitochondrial content are limited to low throughput immunoassays, measurement of mitochondrial DNA, or ...
ORGANISM(S): Mus Musculus 
2020-04-09 | PXD017884 | panorama
Utilizing computational epitope prediction and biochemical assays we predicted and identified high-affinity and/or high-stability KRAS peptides to high prevalence HLA class I molecules. Using single HLA class I allele lines and tumor cell lines in conjunction with MS spectrometry, selected mKRAS epi...
ORGANISM(S): Homo sapiens (Human) 
2021-05-29 | PXD024412 | Pride
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