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ProteomicsDilution Series imputation, LC MS/MS
Missing values in proteomic data sets have real consequences on downstream data analysis and reproducibility. Although several imputation methods exist to handle missing values, no single imputation method is best suited for a diverse range of data sets, and no clear strategy exists for evaluating i...
ORGANISM(S): Homo sapiens (Human) 
2021-05-07 | PXD023012 | Pride
Dia-ms Ovarian cancer Imputation Dilution series 
ProteomicsOvarian cancer imputation analysis, LC MS/MS
Missing values in proteomic data sets have real consequences on downstream data analysis and reproducibility. Although several imputation methods exist to handle missing values, no single imputation method is best suited for a diverse range of data sets, and no clear strategy exists for evaluating i...
ORGANISM(S): Homo sapiens (Human) 
2021-05-07 | PXD023040 | Pride
Dia-ms Ovarianc cancer Tumor Stroma 
ProteomicsPilot data for Imputation, LC-MS/MS
Missing values in proteomic data sets have real consequences on downstream data analysis and reproducibility. Although several imputation methods exist to handle missing values, no single imputation method is best suited for a diverse range of data sets, and no clear strategy exists for evaluating i...
ORGANISM(S): Homo sapiens (Human) 
2021-05-07 | PXD022996 | Pride
Dia-ms Ovarian cancer Imputation 
ProteomicsDistinct phenotypes induced by acute hypoxia and TGF-β1 in human adult cardiac fibroblasts
Myocardial infarctions cause hypoxic injury to downstream tissue and a consequent fibrotic remodeling process to replace injured tissue with a scar. Scar formation occurs through phases of wound healing in which stimuli such as transforming growth factor-beta (TGF-β) drive cardiac fibroblasts to act...
ORGANISM(S): Homo sapiens (Human) 
2024-07-03 | PXD051197 | Pride
Hypoxia Transforming growth factor-beta Cardiac fibrosis Hypoxia-inducible factors Myocardial infarction 
ProteomicsMitoPlex: A Targeted Multiple Reaction Monitoring Assay for Quantification of a Curated Set of Mitochondrial Proteins
Mitochondria are the major source of cellular energy (ATP), as well as critical mediators of widespread functions such as cellular redox balance, apoptosis, and metabolic flux. Methods to quantify mitochondrial content are limited to low throughput immunoassays, measurement of mitochondrial DNA, or ...
ORGANISM(S): Mus Musculus 
2020-04-09 | PXD017884 | panorama
ProteomicsAlendronate and Osteonecrosis of the Jaw
Objectives: Osteonecrosis of the jaw (ONJ), a necrotic bone disease unique to the craniofacial region, is often observed among cancer patients treated with bisphosphonate (BP)-based chemotherapy and becomes a costly and debilitating source of pain and reduced quality of life. Elucidation of clinicop...
ORGANISM(S): Homo sapiens (Human) 
2021-09-10 | PXD024585 | Pride
Ripk3 Osteonecrosis Alendronate Proteomics Wnt/gsk3/b-catenin 
ProteomicsHuman iPSC-derived mononuclear phagocytes restore cognition, neural health, and a subpopulation of hippocampal mossy cells in aging mice
Young blood or plasma and young bone marrow improves cognitive function in aged animals, though the cell type responsible for these regenerative effects remains unknown. This study evaluated the potential of induced pluripotent stem cell-derived mononuclear phagocytes (iMPs) as a therapeutic for ag...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-10 | PXD052723 | Pride
Neural health Induced pluripotent stem cells Hippocampus Mononuclear phagocytes Aging Cognitive decline 
ProteomicsIdentification of Putative Early Atherosclerosis Biomarkers by Unsupervised Deconvolution of Heterogeneous Vascular Proteomes
Coronary artery disease remains a leading cause of death in industrialized nations, and early detection of disease is a critical intervention target in order to effectively treat patients and manage risk. Proteomic analysis of mixed tissue homogenates may obscure subtle protein changes that occur un...
ORGANISM(S): Homo Sapiens 
2021-01-21 | PXD016730 | panorama
ProteomicsPASS00724 - Raw DIA files and libraries used in the manuscript "Identification of a Set of Conserved Eukaryotic Internal Retention Time Standards for Data-Independent Acquisition Mass Spectrometry"
Data independent acquisition files and corresponding library files used to demonstrate the value of a set of conserved, commonly occurring peptide sequences to align chromatographic retention time between spectral libraries and DIA files.
ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932) Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2018-08-23 | MSV000082842 | MassIVE
UnknownEfficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine.
Not available
S-EPMC7787219 | biostudies-literature
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