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MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
UnknownBarium-Promoted Yttria-Zirconia-Supported Ni Catalyst for Hydrogen Production via the Dry Reforming of Methane: Role of Barium in the Phase Stabilization of Cubic ZrO2.
Not available
S-EPMC9118375 | biostudies-literature
UnknownUtility of Lille Score in Predicting 30-Day Survival in Steroid-Treated Alcohol-Associated Hepatitis.
Not available
S-EPMC11341594 | biostudies-literature
UnknownImpact of a Healthcare Provider Educational Intervention on Frequency of Clostridium difficile Polymerase Chain Reaction Testing in Children: A Segmented Regression Analysis.
Not available
S-EPMC5907876 | biostudies-literature
ProteomicsCompetitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma
The pluripotency transcription factor SOX2 is essential for the maintenance of glioblastoma stem cells (GSC), which drive tumor growth and treatment resistance.To understand how SOX2 is regulated in GSCs, we utilized a proteomic approach and identified the E3 ubiquitin ligase TRIM26...
ORGANISM(S): Homo sapiens (Human) 
2021-11-04 | PXD028933 | Pride
Glioblastoma Trim26 E3 ligase Wwp2 Brain cancer Sox2 
UnknownGene expression profiles of ischemic stroke clots retrieved by mechanical thrombectomy are associated with disease etiology.
Not available
S-EPMC9789205 | biostudies-literature
UnknownFormation of recombinant bifunctional fusion protein: A newer approach to combine the activities of two enzymes in a single protein.
Not available
S-EPMC8975109 | biostudies-literature
UnknownInjectable long-acting ivacaftor-loaded poly (lactide-co-glycolide) microparticle formulations for the treatment of cystic fibrosis: In vitro characterization and in vivo pharmacokinetics in mice.
Not available
S-EPMC10843602 | biostudies-literature
MetabolomicsAssociation between altered tryptophan metabolism, plasma aryl hydrocarbon receptor agonists, and inflammatory Chagas disease

Chagas disease causes a cardiac illness characterized by immunoinflammatory reactions leading to myocardial fibrosis and remodeling. The development of Chronic Chagas Cardiomyopathy (CCC) in some patients while others remain asymptomatic is not fully understood, but dysregulated inflammatory resp...

2024-01-11 | MTBLS8390 | MetaboLights
UnknownC57BL/6 substrain differences in formalin-induced pain-like behavioral responses.
Not available
S-EPMC7375808 | biostudies-literature
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