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We have mapped regulatory loci for nearly all protein coding genes in the mammalian genome using microarray measurements from a panel of mouse/hamster radiation hybrids. Proof of principle transfection experiment. Pcdh7 (a gene identified as being a regulator of many genes) is transfected into A23 ...
ORGANISM(S): Homo sapiens 
We used proximity dependent biotin identification (BioID) method to determine cell cycle specific interaction partners of PCDH7. HeLa S3 cells were synchronized to interphase and mitosis using double tymidine block and double thymidine block followed by S-Trityl-L-cysteine (STC) treatment respecti...
ORGANISM(S): Homo sapiens (Human) 
2023-02-27 | PXD029246 | Pride
Monoclonal antibodies targeting PCDH7 inhibit tumor growth and enhance targeted therapy response in non-small cell lung cancer
We identified a critical oncogenic role for Protocadherin 7 (PCDH7), a cell surface protein and member of the Cadherin superfamily in NSCLC. PCDH7 is frequently overexpressed in lung adenocarcinoma (LUAD) and associates with poor clinical outcome. Depletion of Pcdh7 reduces lung tumor burden and pro...
ORGANISM(S): Homo sapiens 
2026-04-30 | GSE235391 | GEO
Identification of cold tumor induction–related markers in pancreatic cancer and the clinical implication of PCDH7
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