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Atopic Dermatitis (AD) is the most common inflammatory skin disease and characterized by a deficient epidermal barrier and cutaneous inflammation. Genetic studies suggest a key role of keratinocytes in AD pathogenesis, but the alterations in the proteome that occur in the entire epidermis have not b...
ORGANISM(S): Homo sapiens (Human) 
2022-10-04 | PXD025431 | Pride
In this study, we used two workflows based on either pressure cycling technology (PCT) or ultrasonication (US) in combination with data independent acquisition (DIA) based mass spectrometry (MS) analysis to quantitatively assess the proteomes of articular cartilage and subchondral bone.
ORGANISM(S): Equus caballus (Horse) 
2022-10-12 | PXD025882 | Pride
Our study pioneers a systematic comparison of DNT and MGA proteomes using cutting-edge analytical workflows. Freshly obtained kidney tissues (acquired via puncture or surgery) underwent pressure cycling technology (PCT)-assisted lysis15, 16. The extracted proteins then underwent proteolysis using a ...
ORGANISM(S): Homo Sapiens 
2025-11-10 | PXD070517 |
Atopic dermatitis epidermis PCT-DIA
To characterize potential biomarkers and underlying mechanisms that prompt pathological complete response (pCR) rate of neoadjuvant chemoradiotherapy (nCRT) in locally advanced rectal cancer (LARC) patients.LARC patients from two hospitals were enrolled with pre-nCRT biopsy tissues examined by press...
ORGANISM(S): Mus musculus 
2025-09-09 | GSE213009 | GEO
Rapid proteotyping of 41 FFPE DLBCL tumor tissues with 2-3 biological replicates using pressure-cycling technology (PCT) and SWATH mass spectrometry.
ORGANISM(S): Homo sapiens (Human) 
2019-10-07 | PXD014943 | Pride
FOSL2 promotes intertumoral infiltration of T Cells and increase pathological complete response rates in locally advanced rectal cancer patients
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