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MetabolomicsApplication of the Protease-Resistant Antimicrobial Peptide R7I, Composed of Natural Amino Acids, as a Functional Food Ingredient for Modulating Intestinal Health

Foodborne pathogenic bacterial infections pose significant challenges to global food safety and public health, while the issue of antimicrobial resistance (AMR) has worsened in recent years, creating an urgent need for safe, natural alternatives to combat foodborne pathogens and associated intest...

2025-11-09 | MTBLS13292 | MetaboLights
TranscriptomicsExpression data from 5CC7 T cells stimulated in vivo
We used microarrays to determine how the quality and quantity of peptide-MHC impact TCR-induced gene expression in vivo. Adoptively transferred 5CC7 T cells were stimulated in vivo with different doses if two peptides: MCC peptide is a strong agonist and 102S peptide is a weak agonist for the 5CC7 T...
ORGANISM(S): Mus musculus 
2015-05-15 | E-GEOD-68893 | biostudies-arrayexpress
ProteomicsLabel-free quantitative phosphoproteomic profiling of cellular response induced by an insect cytokine paralytic peptide
Paralytic peptide (PP) participates in diverse physiological processions as an insect cytokine, such as immunity controls, paralysis induction, regulation of cell morphology and proliferation. To investigate the molecular mechanism underlying those physiological activities, we systematically investi...
ORGANISM(S): Bombyx mori (Silk moth) 
2017-01-02 | PXD004521 | Pride
Phosphoproteomic Bombyx mori Lcmsms 
TranscriptomicsTranscription profiling of human CD14+ monocytes treated with innate defence regulator peptide IDR-1 in the presence/absence of lipopolyssacharide
Effect of peptide IDR-1 on CD14+ human monocytes. >br< >br< Effect of peptide IDR-1 on LPS-induced responses in CD14+ human monocytes.>br< >br< Human peripheral blood mononuclear cells (PBMC) were treated with innate defence regulator peptide IDR-1 in the presence and absence of LPS (purified from P...
ORGANISM(S): Homo sapiens 
2007-04-10 | E-FPMI-8 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of endotoxin-stimulated human monocytic cells in presence and absence of host defense peptide LL-37
The objective of the study was to evaluate transcriptional response of endotoxin-stimulated human monocytic cells in presence and absence of host defense peptide LL-37. A functional genomics approach was used to establish a temporal transcriptional profile and identify differentially expressed gene...
ORGANISM(S): Homo sapiens 
2006-08-01 | E-FPMI-4 | biostudies-arrayexpress
ProteomicsAntibody-free multiplex measurement of 23 human cytokines in primary cell culture secretome using targeted multiple reaction monitoring mass spectrometry
Cytokines are commonly measured by immunoassays, which have limited multiplexing capacity, are costly and can exhibit cross-reactivity. Although multiple reaction monitoring (MRM) mass spectrometry is a cost-effective method for multiplex measurement of peptides, the ability to detect the relatively...
ORGANISM(S): Homo sapiens (Human) 
2020-02-19 | PXD015407 | Pride
Human Cytokine Secretome 
ProteomicsGS1 Cytokine Array Analysis of Primary Human Macrophages Polarized to M0, M1, M2, 14P-TAM, and 14P-RT TAM states
A comparative analysis of 20 analytes from matched primary macrophages polarized to various states was performed to characterize a novel polarization method and compare it to classically polarized M0, M1, and M2 macrophages. Macrophages polarized by the xenoline JX14P and its matched in vivo radiati...
ORGANISM(S): Homo sapiens 
2025-12-31 | E-MTAB-15227 | biostudies-arrayexpress
TranscriptomicsRescue Of Dysfunctional Autophagy By Peptide IDR-1018 Attenuates Hyperinflammatory Phenotype Of Cystic Fibrosis Cells (RNA-seq)
Genome-wide gene expression was measured in peripheral blood mononuclear cells (PBMCs) from patients with cystic fibrosis (CF) after treatment in vitro with the flagellin protein fliC, and/or synthetic peptide IDR-1018 to assess patterns of gene expression. The patterns of gene expression suggest th...
ORGANISM(S): Homo sapiens 
2012-11-20 | E-GEOD-35394 | biostudies-arrayexpress
TranscriptomicsMouse cytokine antibody array
Tumors of hematopoietic stem cell transplantation (HSCT) or control mice were collected at day 14 post transplantation. Comprehensive analysis of cytokine levels were performed by using commercially available RayBio Mouse Cytokine Array G series III and IV (RayBiotech, Inc.) according to manufacture...
ORGANISM(S): Mus musculus 
2013-08-28 | E-MTAB-1761 | biostudies-arrayexpress
ProteomicsLongitudinal Olink affinity proteomics profiling of cytokine release syndrome in myeloma patients receiving BCMA-directed CAR-T therapy
This submission contains de-identified Olink NPX affinity proteomics data from longitudinal peripheral blood samples collected from patients with relapsed/refractory multiple myeloma treated with BCMA-directed CAR-T therapy (ide-cel or cilta-cel) in a prospective single-center pilot study. Samples w...
ORGANISM(S): Homo sapiens (Human) 
2026-04-28 | PAD000041 | Pride
Car-t Myeloma Wearables Cytokines Crs 
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