Sort   by:  
 Page size 
TranscriptomicsRNA sequencing of primary thymic, bone and skin mesenchymal cells
Purpose : Elucidate post-natal role of SCA1+ thymic mesenchymal cells (tMCs) and evaluate the functional overlap between thymic, bone and skin MCs. Method : By high speed cell sorting, we isolated primary MCs (Lin- SCA1+ cells) from mouse thymus, bone and skin. We extracted their respective total RN...
ORGANISM(S): Mus musculus 
2016-02-26 | E-GEOD-73175 | biostudies-arrayexpress
TranscriptomicsDifferential features of Aire-induced and Aire-independent promiscuous gene expression in thymic epithelial cells
Promiscuous gene expression (pGE) of numerous self-antigens in thymic epithelial cells (TEC) enables the elimination of self-reactive T cells. The autoimmune regulator (Aire) is the only known molecular determinant driving pGE in the thymus but the existence of Aire-independent mechanisms has been i...
ORGANISM(S): Mus musculus 
2015-05-19 | E-GEOD-65617 | biostudies-arrayexpress
ProteomicsLC-MSMS of 3 DLBCL cell lines (class I immunopeptidome and whole proteome)
Accumulating evidence indicates that alternative translation events occur in all cell types, suggesting that the proteome is more complex than previously anticipated. We elected to broaden the repertoire of human cryptic proteins by designing an approach combining ribosome profiling, which gives a p...
ORGANISM(S): Homo sapiens (Human) 
2020-11-16 | PXD020620 | Pride
Lc-msms Dlbcl Hbl-1 Dohh2 Immunopeptidome Proteome And su-dhl-4 Mhc class i 
TranscriptomicsEffect of LMP7 and MECL1-immunoproteasome subunits deficiency on the transcriptome of mouse bone marrow-derived dendritic cells
As regulators of protein degradation, proteasomes regulate practically all cellular functions. It is therefore logical to assume that replacement of the constitutive proteasome (CP) by its IFN- inducible homolog immunoproteasome (IP) could have far reaching effects on cell function. Accordingly, re...
ORGANISM(S): Mus musculus 
2014-07-02 | E-GEOD-52616 | biostudies-arrayexpress
TranscriptomicsTranscriptome sequencing of neonatal thymic epithelial cells.
Purpose: In all vertebrates, the thymus is necessary and sufficient for production of classic adaptive T cells. The key components of the thymus are cortical and medullary thymic epithelial cells (cTECs and mTECs). Despite the capital role of TECs, our understanding of TEC biology is quite rudimenta...
ORGANISM(S): Mus musculus 
2013-05-07 | E-GEOD-44945 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of mouse wild type and Baf250a delta/delta primary stromal cell cultures
Global gene expression profiles of primary Baf250a delta/delta and WT FL-derived stromal cell cultures.

Normalized data files with gene level identifiers are available as additional files on the FTP site for this experiment. Background corrections and normalisations were performed using RMA ...
ORGANISM(S): Mus musculus 
2010-06-05 | E-TABM-990 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of dendritic cells derived from the bone marrow of wild type and Lmp7-/-Mecl1-/- mice
Comparison of the MHC I peptidome and of the transcriptome of dendritic cells derived from WT and Lmp7-/-Mecl1-/- mice bone marrow
ORGANISM(S): Mus musculus 
2010-07-22 | E-TABM-750 | biostudies-arrayexpress
GenomicsNon-coding regions are the main source of tumor-specific antigens [mouse]
Non-coding regions are the main source of tumor-specific antigens [mouse]
PRJNA435886 | ENA
TranscriptomicsTGF-beta/Smad3-dependent gene expression analysis in naive CD4 T cells
Investigation of transcript level modulation in unstimulated and TGF-beta treated (with or without superimposed T-cell receptor and CD28 stimulation) naive CD4 T cells from wild type or Smad3-deficient littermate mice. Smad3 is a critical signaling molecule and transcription factor downstream of TGF...
ORGANISM(S): Mus musculus 
2012-08-31 | E-GEOD-40494 | biostudies-arrayexpress
ModelsCaron2010_mTORsignalingNetwork_ActivityFlow
This model originates from BioModels Database: A Database of Annotated Published Models (http://www.ebi.ac.uk/biomodels/). It is copyright (c) 2005-2011 The BioModels.net Team. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model ha...
2005-01-01 | MODEL1012220004 | BioModels
Sort   by:  
 Page size