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ProteomicsLabel-free shotgun proteomics of S. cerevisiae producing starch-like glucans
The synthesis of starch-like glucans can be reconstituted in S. cerevisiae using the genes from Arabidopsis thaliana: heterologous expression of SS1 to SS4, BE2, BE3, ISA1, and ISA2, together with a bacterial ADPglucose pyrophosphorylase gene for substrate provision in yeast strain 29, yielded insol...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-09-05 | PXD032241 | Pride
Lc-ms/ms Progenesisqi Yeast 
TranscriptomicsArray-CGH screening of pediatric T-lymphoblastic leukemias (n=73)
DNA copy-number profiling of 73 T-ALLs Keywords: Genetic modification Comparison of tumor DNA (tumor) versus control DNA (pool of lymphocyte DNA from 10 healthy donors). Whole-genome screening for DNA copy-number aberrations using array-based comparative genomic hybridization (aCGH). Tumor DNA label...
ORGANISM(S): Homo sapiens 
2007-08-25 | E-GEOD-8738 | biostudies-arrayexpress
TranscriptomicsMemory CD8+ T cells require stress-levels of acetate for optimal function
How systemic metabolic alterations during acute infections impact immune-cell function remains poorly understood. Hess and colleagues demonstrate that acetate rapidly increases during infections, which drives acetylation of GAPDH in memory CD8+ T cells and thereby catalyzes the rapid recall response...
ORGANISM(S): Mus musculus 
2016-05-18 | E-GEOD-79600 | biostudies-arrayexpress
ProteomicsPD-1-targeted immunotherapy in NASH-triggered liver cancer induces pro-tumorigenic environment through CD8+PD-1+ T-cells
Immunotherapy has opened hitherto unknown possibilities to treat cancer. Whereas some cancer types (e.g. melanoma) can be efficiently treated, others lack measurable positive effects (e.g. PDAC). Moreover, stratification of responders/non-responders is only possible in some cancer types (e.g. melano...
ORGANISM(S): Mus musculus (Mouse) 
2021-03-03 | PXD017236 | Pride
Immunotherapy Cd8+pd1+ Nash 
UnknownFKBP5 genotype-dependent DNA methylation and mRNA regulation after psychosocial stress in remitted depression and healthy controls.
Not available
S-EPMC4360217 | biostudies-literature
UnknownA review of Hyphodiscaceae.
Not available
S-EPMC10277273 | biostudies-literature
UnknownDiagnostic and prognostic values of the QRS-T angle in patients with suspected acute decompensated heart failure.
Not available
S-EPMC7373892 | biostudies-literature
UnknownPostoperative cellular stress in the kidney is associated with an early systemic γδ T-cell immune cell response.
Not available
S-EPMC6030780 | biostudies-literature
UnknownEZH2 Inhibition Compromises α4-1BB-Mediated Antitumor Efficacy by Reducing the Survival and Effector Programming of CD8+ T Cells.
Not available
S-EPMC8683156 | biostudies-literature
UnknownHuman T cells loaded with superparamagnetic iron oxide nanoparticles retain antigen-specific TCR functionality.
Not available
S-EPMC10470061 | biostudies-literature
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