Phosphatidylinositol 3-phosphate

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CHEBI:26034 (1)

Metabolite Name

Taurine (6)
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1-oleoyl-2-myristoyl-sn-glycero-3-phosphocholine (3)
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Modelling Approach

Ordinary differential equation model (1)

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Lab affiliation

Molecular Cell Biology of Autophagy Laboratory, The Francis Crick Institute, London, United Kingdom (2)
MRC - Laboratory of Molecular Biology (2)
Laboratory of Fungal Pathogenesis, Centre for DNA Fingerprinting and Diagnostics (CDFD), Hyderabad, India (2)
Institute of Zoology and Biomedical Research Laboratory of Physiology and Toxicology of Reproduction, Faculty of Biology, Jagiellonian University, Krakow, Poland (1)
Microbiome Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea (1)
Protein Expression and Modification Division Research Department New England Biolabs United States (1)
Department of Molecular Medicine, Max Planck Institute of Biochemistry, Martinsried, Germany Current address: Institute of Diabetes and Regeneration Research, Helmholtz Diabetes Center, Helmholtz Zentrum München, Neuherberg, Germany (1)
Cambridge Institute for Medical Research (CIMR), Department of Genomic Medicine, University of Cambridge, Cambridge CB2 0XY (1)
Biologie II Albert-Ludwigs-Universität Freiburg Schänzlestr. 1 79104 Freiburg Germany (1)
R602,128, Academia Road Sec. 2, Nankang, Taipei 115, Taiwan (1)
Associate Professor, Molecular and Cellular Biology Associate Professor, Genetics - GIDP Associate Professor, BIO5 Institute (1)
Max Perutz Labs, Vienna BioCenter, Dr. Bohr-Gasse 9, Vienna, Austria (1)
Department of Biochemistry, Microbiology and Immunology University of Ottawa, Ottawa, Canada (1)
Institute of Parasitology, McGill University, Sainte-Anne-de-Bellevue, QC H9X 3V9, Canada (1)
Institut of Physiology, Faculty of Medicine, TU Dresden (1)
Institute for Biochemistry and Molecular Biology, University of Bonn (1)
Plant Molecular Biology Lab, Malopolska Centre of Biotechnology, Jagiellonian University (1)
Department of Biochemistry and Microbiology, University of Chemistry and Technology, Prague, Technická 5, 166 28 Prague, Czech Republic (1)
Huazhong Agricultural University (1)
Department of Structural and Computational Biology, Max Perutz Labs, Campus Vienna Biocenter 5, 1030 Vienna, Austria (1)
Proteomics and Metabolomics Facility, University of Nebraska - Lincoln (1)
University of Victoria (1)
Basic Immune System of Plants / Protein Mass Spectrometry Max Planck Institute for Plant Breeding Research Carl-von-Linne-Weg 10, 50829 Cologne, Germany (1)
Head of Proteomics (1)

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NPC1 regulates the distribution of phosphatidylinositol 4 kinases at Golgi and Lysosome membranes

Cholesterol and phosphoinositides (PI) are two critically important lipids that are found in cellular membranes and dysregulated in many disorders. Therefore, uncovering molecular pathways connecting these essential lipids may offer new therapeutic insights. We report that loss of function of lysoso...

2021-09-15 | MTBLS2612 | MetaboLights

Label-free quantitative plasma membrane proteome analysis of Candida glabrata wild-type and Cgvps34∆ (lacks phosphatidylinositol 3- phosphate kinase, CgVps34) strains. Label-free quantitative plasma membrane proteome analysis of Candida glabrata wild-type and Cgvps34∆ (lacks phosphatidylinositol 3- phosphate kinase, CgVps34) strains.

The project is aimed at characterizing the effect of loss of phosphatidylinositol 3- phosphate kinase (CgVps34) on the plasma membrane proteome of Candida glabrata.

ORGANISM(S): Candida glabrata (Yeast) (Torulopsis glabrata)

2024-02-19 | PXD042056 | Pride

In vitro reconstitution of Sgk3 activation by phosphatidylinositol-3-phosphate

Serum- and glucocorticoid-regulated kinase 3 (Sgk3) is activated by the phospholipid 19 phosphatidylinositol-3-phosphate (PI3P) downstream of growth factor signaling and 20 by Vps34-mediated PI3P production during autophagy. Upregulation of Sgk3 activity 21 has been linked to a number of human cance...

ORGANISM(S): Homo sapiens (Human)

2021-09-22 | PXD025327 | Pride

Kinase Sgk3 Hdx-ms Pi3p

Phosphatidylinositol 3-phosphate (PI3P) interactome analysis under varied iron conditions in Candida glabrata.

The project is aimed at identifying proteins that interact with PI3P in low-iron, regular-iron and high-iron grown Candida glabrata cells.

ORGANISM(S): Candida glabrata (Yeast) (Torulopsis glabrata)

2024-02-19 | PXD042058 | Pride

Bathophenanthroline disulfonate (bps) Lc-ms/ms. Candida glabrata Phosphatidylinositol 3-phosphate (pi3p)

Ca2+-regulated pool of phosphatidylinositol-3-phosphate produced by phosphatidylinositol 3-kinase C2alpha on neurosecretory vesicles.

Not available

S-EPMC2592681 | biostudies-literature

In vitro reconstitution of Sgk3 activation by phosphatidylinositol 3-phosphate.