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TranscriptomicsGene expression profiles at single cell level of nucleotides optimized WT or S449A PTPN22 in J.Lck WT or J.Lck Y192F Jurkat cells
Protein Tyrosine Phosphatase Non-receptor type 22 (PTPN22) is encoded by a major autoimmunity gene and is a known inhibitor of T cell receptor (TCR) signaling. PTPN22 Ser449 is a novel phosphorylation site. Here we used optimized coding sequences (CDS) of PTPN22 WT or S449A eukaryotic expression vec...
ORGANISM(S): Homo sapiens 
2025-04-25 | GSE265961 | GEO
GenomicsGene expression profiles at single cell level of nucleotides optimized WT or S449A PTPN22 in J.Lck WT or J.Lck Y192F Jurkat cells
Gene expression profiles at single cell level of nucleotides optimized WT or S449A PTPN22 in J.Lck WT or J.Lck Y192F Jurkat cells
PRJNA1105053 | ENA
ProteomicsPhosphoproteome profiling using the isobaric carrier without the need for phosphoenrichment
Phosphorylation is a crucial component of signaling cascades in a cell. It controls various biological cellular functions such as cell growth and apoptosis. Due to the low stoichiometry of phosphorylaion, enrichment of phosphopeptide prior to LC-MS/MS is necessary for comprehensive phosphoproteome a...
ORGANISM(S): Homo sapiens (Human) 
2022-03-07 | PXD028490 | Pride
Isobaric labeling Tmt Carrier Phosphoproteome Quantitative proteomics 
UnknownDifferences in intrinsic aerobic capacity alters sensitivity to ischemia-reperfusion injury but not cardioprotective capacity by ischemic preconditioning in rats.
Not available
S-EPMC7591019 | biostudies-literature
ProteomicsIdentification of putative phosphorylation substrates of BRI1 in response to brassinolide and sucrose
Plants respond to various external and internal stimuli by activating signal transduction pathways. The plasma membrane, acting as the cell boundary, provides a platform for various signaling components. These include cell surface receptor-like kinases, intrinsic transporters, membrane-anchored prot...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-05-07 | PXD052599 | Pride
Sucrose Phosphorylaion Kinase-target Branssinolide Plasma membrane 
ProteomicsPhosphorylation landscape on time-resolved SYR1-dependent systemin signaling pathway
Systemin was identified in 1991 as the first plant signaling peptide, and is required for defense against insect herbivores and necrotrophic pathogens in tomato plants. Systemin was first conceived as a hormone-like, long-distance messenger mediating the activation of systemic defense responses far ...
ORGANISM(S): Solanum peruvianum 
2025-06-17 | PXD054229 | Pride
Signaling transduction Phosphorylaion Time course Systemin Syr1 
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