Sort   by:  
 Page size 
ProteomicsDesign and evaluation of a cyclobutane diazirine alkyne tag for photoaffinity labeling in cells
Alkyl diazirines are frequently used in photoaffinity labeling to trap and identify small molecule–protein interactions. How-ever, the alkyl diazirine can preferentially label acidic amino acids and acidic protein surfaces in a pH-dependent manner, presumably via a long-lived alkyl diazo intermediat...
ORGANISM(S): Homo sapiens (Human) 
2024-01-04 | PXD035954 | Pride
Cereblon Diazirine Thalidomide Photoaffinity labeling Binding site mapping 
UnknownPhotoaffinity labeling of plasma proteins.
Not available
S-EPMC6270137 | biostudies-literature
UnknownClick-Addressable Cassette for Photoaffinity Labeling.
Not available
S-EPMC5807873 | biostudies-literature
ProteomicsLabeling preferences of diazirines with protein biomolecules
Diazirines are widely used in photoaffinity labeling (PAL) to trap non-covalent interactions with biomolecules. However, design and interpretation of PAL experiments is challenging without a molecular understanding of the reactivity of diazirines with protein biomolecules. Here, we report a system...
ORGANISM(S): Homo sapiens (Human) 
2022-07-20 | PXD025140 | Pride
Sknsh cells Diazirine Photoaffinity labeling Proteomics Binding sites 
UnknownEn route to photoaffinity labeling of the bacterial lectin FimH.
Not available
S-EPMC2956469 | biostudies-literature
UnknownFluorogenic Photoaffinity Labeling of Proteins in Living Cells.
Not available
S-EPMC6630177 | biostudies-literature
UnknownGlutathione Transferase Photoaffinity Labeling Displays GST Induction by Safeners and Pathogen Infection.
Not available
S-EPMC10799724 | biostudies-literature
UnknownDesign and Evaluation of a Cyclobutane Diazirine Alkyne Tag for Photoaffinity Labeling in Cells.
Not available
S-EPMC11647570 | biostudies-literature
UnknownGold nanoparticle-based multivalent carbohydrate probes: selective photoaffinity labeling of carbohydrate-binding proteins.
Not available
S-EPMC5530003 | biostudies-literature
ProteomicsProteome-wide profiling of olaparib interactors using a biotinylated photoaffinity probe
Olaparib is a widely used PARP inhibitor for the treatment of BRCA-mutated cancers. To comprehensively understand the drug's clinical impact, measuring its interactions with intended on- and off-targets is crucial. In this study, olaparib's on- and off-targets were profiled using photoaffinity label...
ORGANISM(S): Homo sapiens (Human) 
2025-02-04 | PXD060372 | Pride
Parp inhibitors Photoaffinity labeling Chemical proteomics Olaparib 
Sort   by:  
 Page size