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The treatment of colorectal cancer (CRC) is an unmet medical need in absence of early diagnosis. Here, upon characterizing cancer-specific transposable element-driven transpochimeric gene transcripts (TcGTs) produced by this tumor, we found that expression of the hominid-restricted retrogene POU5F1B...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD028035 | Pride
The treatment of colorectal cancer (CRC) is an unmet medical need in absence of early diagnosis. Here, upon characterizing cancer-specific transposable element-driven transpochimeric gene transcripts (TcGTs) produced by this tumor, we found that expression of the hominid-restricted retrogene POU5F1B...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD028036 | Pride
Advanced prostate cancer initially responds to hormonal treatment, but ultimately becomes resistant and requires more potent therapies. One mechanism of resistance seen in 10% of these patients is through lineage plasticity, which manifests in a partial or complete small cell or neuroendocrine pros...
ORGANISM(S): Homo sapiens (Human) 
2020-11-04 | PXD016861 | Pride
Knockdown of DHRS7 in the prostate cancer cell line LNCaP was performed for 24h, 36h, and 48h using siRNA.
ORGANISM(S): Homo sapiens (Human) 
2022-07-07 | PXD031229 | Pride
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