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ProteomicsDIA-MS to characterise lung cancer proteomic signature in blood plasma
DIA-MS plasma proteomics of a cohort of 490 lung cancer cases and 124 age-, sex-match controls collected post-diagnosis and pre-treatments. The cohort covers all stages, major histologies and smoking exposures and were recruited from Princess Margaret Cancer Centre’s Lung-CALIBRE program (Lung cance...
ORGANISM(S): Homo sapiens (Human) 
2026-10-26 | PXD072886 | Pride
Dia-ms Lung cancer Plasma Proteomics 
ProteomicsSWATH DIA optimisation for plasma proteomics
The aim of this project was to benchmark the ability of a variety of SWATH/DIA workflows to detect protein abundance differences in a human plasma matrix, using a mixedspecies spike-in model.
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2026-10-06 | PXD075041 | Pride
Dia  plasma  benchmarking  human  e. coli 
ProteomicsFast proteomics with dia-PASEF and analytical flow-rate chromatography
The presented approach is a combination of analytical flow rate chromatography with ion mobility separation of peptide ions, data-independent acquisition, and raw data processing using the DIA-NN software suite, to conduct fast, low-cost proteomic experiments that only require moderate sample amount...
ORGANISM(S): Escherichia Coli (ncbitaxon:562) Homo Sapiens (ncbitaxon:9606) 
2024-10-24 | MSV000096202 | MassIVE
ProteomicsMethod development for simplified High-Throughput Plasma Proteomics
We developed a simplified proteomics sample preparation method that increased the sensitivity and reproducibility of large-scale plasma samples. Peptide loss was reduced while sensitivity was increased by eliminating the peptide clean-up step and using disposable trap column tips. The simplified Hig...
ORGANISM(S): Homo sapiens (Human) 
2023-04-03 | PXD038669 | Pride
Shtpp Simplified high-throughput plasma proteomics 
ProteomicsNEAT PLASMA PROTEOMICS: GETTING THE BEST OUT OF THE WORST
Plasma proteomics holds immense potential for clinical research and biomarker discovery, serving as a non-invasive "liquid biopsy" for tissue sampling. Mass spectrometry (MS)-based proteomics, thanks to improvement in speed and robustness, emerges as an ideal technology for exploring the plasma prot...
ORGANISM(S): Homo sapiens (Human) 
2024-08-14 | PXD047857 | Pride
Plasma Dia-nn Dia Extracellular vesicles Timstof pro 
ProteomicsFast proteomics with dia-PASEF and analytical flow-rate chromatography
The presented approach is a combination of analytical flow rate chromatography with ion mobility separation of peptide ions, data-independent acquisition, and raw data processing using the DIA-NN software suite, to conduct fast, low-cost proteomic experiments that only require moderate sample amount...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2023-07-03 | PXD040205 | Pride
Short gradient Dia-pasef Timstof Fast methods Plasma proteomics High-throughput Covid-19 
ProteomicsMicroflow SWATH data analysed with DIA-NN
We have developed DIA-NN, an integrated software suite for fully-automated processing of raw SWATH/DIA data. DIA-NN enables deep and confident proteome coverage with fast chromatographic methods, paving the way for a new generation of high-throughput proteomics. This data set illustrates the capabil...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) 
2019-11-06 | PXD014690 | Pride
Gas-phase fractionation Dia K562 Swath Yeast Plasma High-throughput proteomics 
ProteomicsAnalysis of novel plasma protein biomarkers in sepsis using DIA mass spectrometry
This study used DIA mass spectrometry to identify novel plasma protein biomarkers for sepsis, aiming to search for new diagnostic targets for sepsis and after administration of atorvastatin and vitamin D.
ORGANISM(S): Mus musculus (Mouse) 
2026-04-13 | PXD060677 | Pride
 protein biomarkers Epsis  dia  plasma 
ProteomicsRecombinant SWATH library for identification of low abundant human plasma proteins
Recombinant SWATH library for identification of low abundant human plasma proteins
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-11-04 | MSV000086411 | MassIVE
ProteomicsMouse organ specific spectral library and DIA analysis of the plasma proteome
The plasma proteome is highly dynamic and variable, composed of proteins derived from surrounding tissues and cells. To investigate the complex processes that contribute to the plasma proteome homeostasis we developed a mass spectrometry based proteomics strategy to infer the origin of proteins dete...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2017-11-08 | MSV000081695 | MassIVE
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