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TranscriptomicsRNA expression data from glomeruli lacking von Hippel-Lindau protein in podocytes
We and others have previously shown that glomerular endothelial cells and podocytes express hypoxia-inducible transcription factors (HIFs). HIFs bind to hypoxia response elements in target genes, such as vascular endothelial growth factor, which is continually produced by podocytes throughout life....
ORGANISM(S): Mus musculus 
2010-08-03 | E-GEOD-20235 | biostudies-arrayexpress
ProteomicsPodocyte Focal Adhesion Proteome
Expression proteomics analysis of focal adhesion complexes isolated from a human immortalized podocyte cell line.
ORGANISM(S): Homo sapiens (Human) 
2018-12-14 | PXD010626 | Pride
Human Podocyte Glomerulus Kidney Lc-ms/ms 
GenomicsHuman iPSC-derived glomeruli provide an advanced model to interrogate podocyte biology and accurately recapitulate podocytopathy
Human iPSC-derived glomeruli provide an advanced model to interrogate podocyte biology and accurately recapitulate podocytopathy
PRJNA438893 | ENA
TranscriptomicsThe change of mRNA expression in murine immortalized podocyte after miR-26a silencing
The change of mRNA expression in murine immortalized podocyte were analyzed after miR-26a silencing. These results provide a basical information of molecular pathology in podocyte biology. Mouse podocytes immortalized by temperature sensitive SV40 were used. Podocyte cultures grown at 33 °C were try...
ORGANISM(S): Mus musculus 
2014-10-01 | E-GEOD-51210 | biostudies-arrayexpress
TranscriptomicsMolecular fingerprint of the podocyte reveals novel gene regulatory networks
The thorough characterization of the transcriptome of endogenous podocytes has been hampered by low yields of cell isolation procedures. Here we introduce a double fluorescent reporter mouse model combined with an optimized bead perfusion protocol and efficient single cell dissociation yield...
ORGANISM(S): Mus musculus 
2012-11-30 | E-GEOD-39441 | biostudies-arrayexpress
TranscriptomicsHuman iPSC-derived glomeruli provide an advanced model to interrogate podocyte biology and accurately recapitulate podocytopathy
Podocytes are highly specialised cells within the glomeruli of the kidney that maintain the filtration barrier by forming interdigitating foot processes and slit-diaphragms. Disruption to these features result in proteinuria and glomerulosclerosis. Studies into podocyte biology and disease have prev...
ORGANISM(S): Homo sapiens 
2018-12-04 | GSE111992 | GEO
ProteomicsAnalysis of podocyte adhesome proteomes
To elucidate potential mechanisms how EPB41L5 modulates integrin adhesion complex maturation, we performed quantitative SILAC-based integrin adhesome proteomics. For MS analysis of the podocyte adhesome, EPB41L5 or Luciferase (as negative control) was transient expressed in SILAC labeled podocytes b...
ORGANISM(S): Homo sapiens (Human) 
2021-08-05 | PXD023821 | Pride
Lc-msms Ecm Adhesome Human 
ProteomicsMitochondrial IntegrityMitochondrial Integrity Modulates mTOR Signaling and Podocyte Function Modulates mTOR Signaling and Podocyte Function
Mitochondrial dysfunction has emerged as a key contributor to the pathogenesis of steroid-resistant nephrotic syndrome (SRNS) and genetic focal-segmental glomerulosclerosis (FSGS). This study explores the role of mitochondrial integrity in podocyte biology, focusing on the impact of OMA1, a critical...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-26 | PXD071171 | Pride
Mitochondria Glycolysis 
TranscriptomicsThe change of mRNA expression in murine immortalized podocyte after miR-26a silencing
The change of mRNA expression in murine immortalized podocyte were analyzed after miR-26a silencing. These results provide a basical information of molecular pathology in podocyte biology.
ORGANISM(S): Mus musculus 
2014-10-01 | GSE51210 | GEO
UnknownMetabolism, energetics, and lipid biology in the podocyte - cellular cholesterol-mediated glomerular injury.
Not available
S-EPMC4196552 | biostudies-literature
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