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MetabolomicsComprehensive multi-omics analysis reveals the influence of epigenetic mechanisms on porcine oocyte maturation
In vitro maturation (IVM) oocyte is a key component of assisted reproduction in pigs. Asynchronous nucleoplasmic maturation and incomplete cytoplasmic maturation is one of the key factors for impaired maturation and quality of oocytes matured in vitro. Although Single-omics techniques have been appl...
2025-08-27 | MTBLS12325 | MetaboLights
MetabolomicsCycloleucine disturbs functions of porcine Sertoli cells via modulating gene expression and metabolism

Cycloleucine (CL) is a methyl donor inhibitor. Our previous findings showed that CL could affect meiotic maturation and developmental potency of porcine oocytes by reducing nucleic acid N6-methyladenosine (m6A) epigenetic modification level. However, the effects of CL on porcine male reproduction...

2025-09-13 | MTBLS12990 | MetaboLights
TranscriptomicsExpression data from prepubertal and adult derived porcine oocytes
Oocyte developmental potential is progressively obtained as females approach puberty. Therefore, oocytes derived from prepubertal females are less developmentally competent, indicated by decreased embryonic development, compared to oocytes derived from adult females. To investigate mechanisms invol...
ORGANISM(S): Sus scrofa 
2009-12-30 | E-GEOD-11590 | biostudies-arrayexpress
ProteomicsQuantitative proteomic analysis of both fresh and vitrified porcine GV oocytes during in vitro maturation
In this study, we used tandem mass tag (TMT)-based quantitative approach to acquire proteomic profiles of porcine GV and MII oocytes and MII oocytes vitrified at the GV stage.
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2021-07-01 | PXD023107 | Pride
Oocytes Tmt Vitrification Pig Ivm 
GenomicsSpermidine promotes meiotic maturation of porcine oocytes
Spermidine promotes meiotic maturation of porcine oocytes
PRJNA899034 | ENA
ProteomicsImpact of media supplementation on a transcriptional activity of porcine embryos produced in vitro
The production of embryos in vitro caused a revolution in the field of assisted reproduction technologies, which currently allows the manipulation and selection of embryos before implantation. One of the key aspects of this process is the maturation of oocytes in a controlled in vitro environment. I...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2023-09-25 | PXD045481 | Pride
Dmem Maturation medium Oocyte Fli Porcine 
GenomicsPorcine oocytes matured in a chemically defined medium are transcriptionally active
Porcine oocytes matured in a chemically defined medium are transcriptionally active
PRJNA898618 | ENA
Genomicskey histone modifications in porcine oocytes and early embryos
key histone modifications in porcine oocytes and early embryos
PRJNA687245 | ENA
ProteomicsMelatonin Rescues Triclosan-Disrupted Porcine Oocyte Meiosis via Suppression of p53-Mediated Apoptosis
This study investigates the toxic effects of the environmental contaminant triclosan (TCS) on porcine oocyte meiosis and the protective role of melatonin (MT). Using an in vitro maturation model, TCS was found to impair polar body extrusion and cumulus expansion, while inducing oxidative stress, mit...
ORGANISM(S): Sus scrofa (Pig) 
2025-11-17 | PXD068303 | Pride
Porcine oocytes  melatonin  triclosan  apoptosis  p53 
GenomicsTranscriptome profiles of porcine oocytes with different developmental competence
Transcriptome profiles of porcine oocytes with different developmental competence
PRJNA533463 | ENA
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