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UnknownCost-effectiveness of Crohn's disease post-operative care.
Not available
S-EPMC4814750 | biostudies-literature
TranscriptomicsDifferential Response Following Spinal Cord Injury in EphA4 Knockout
Mice lacking the developmental axon guidance molecule EphA4 have previously been shown to exhibit extensive axonal regeneration and functional recovery following spinal cord injury. To assess mechanisms by which EphA4 may modify the response to neural injury, a microarray was performed on spinal co...
ORGANISM(S): Mus musculus 
2012-05-23 | E-GEOD-34430 | biostudies-arrayexpress
ProteomicsPptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis
Mitochondrial proteins are replete with phosphorylation; however, the origin, abundance, and functional relevance of these modifications are largely unclear. Nonetheless, mitochondria possess multiple resident phosphatases, suggesting that protein dephosphorylation may be broadly important for mitoc...
ORGANISM(S): Mus musculus (Mouse) 
2019-05-29 | PXD012743 | Pride
Mitochondia Pptc7 Phosphoproteome 
TranscriptomicsTranscription profiling of human monocytes after treatment vehicle, isotype control antibody, TREM1 antibody, LPS, isotype control antibody plus LPS and TREM1 antibody plus LP to invesigate innate immune responses to TREM-1 activation
TREM-1 is an orphan immunoreceptor expressed on monocytes, macrophages, and neutrophils. TREM-1 associates with and signals via the adapter protein DAP12/TYROBP, which contains an immunoreceptor tyrosine-based activation motif (ITAM). TREM-1 activation by receptor cross-linking is pro-inflammatory, ...
ORGANISM(S): Homo sapiens 
2008-04-05 | E-GEOD-9988 | biostudies-arrayexpress
UnknownThin silk fibroin films as a dried format for temperature stabilization of inactivated polio vaccine.
Not available
S-EPMC7176408 | biostudies-literature
TranscriptomicsDysregulated deltaNp63alpha negatively regulates p73-mediated maspin expression
The p53 homologue, p63, is critical for normal epidermal development. While overexpression of deltaNp63alpha has been reported in squamous cell cancers, the contribution of p63 to cancer pathogenesis remains unclear. We previously demonstrated that overexpressed deltaNp63alpha aberrantly maintains p...
ORGANISM(S): Mus musculus 
2013-02-26 | E-GEOD-34862 | biostudies-arrayexpress
MetabolomicsAlignment of multiple metabolomics LC-MS datasets from disparate diseases to reveal fever-associated metabolites

Acute febrile illnesses are still a major cause of mortality and morbidity globally, particularly in low to middle income countries. The aim of this study was to determine any possible metabolic commonalities of patients infected with disparate pathogens that cause fever. Three liquid chromatogra...

2023-07-17 | MTBLS4895 | MetaboLights
ProteomicsExtrarenal ?-klotho expression in human tissues
?-Klotho has emerged as a powerful regulator of the ageing process. To-date, the expression profile of ?-Klotho in human tissues is unknown and its existence in some human tissue types is subject to much controversy. Objective: This is the first study to characterize system-wide tissue expression of...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080719 | MassIVE
GenomicsWhole Genome Bisulfite Sequencing of CLDN6High vs CLDN6Low Sorted EpiSCs and APSD, and WT vs Pbx1-KO EpiSCs
The experiment was designed to assess the DNA methylation differences between CLDN6Low vs CLDN6High EpiSCs and APSD, as well as WT vs Pbx1-KO EpiSCs. Based on analysis of RNAseq data and GO, we narrowed down our focus to DNA methylation effects influencing lineage biases. We performed WGBS analysi...
ORGANISM(S): Mus musculus 
2025-04-28 | E-MTAB-13574 | biostudies-arrayexpress
ProteomicsGlobal proteomics indicates subcellular-specific anti-ferroptotic responses to ionizing radiation
Cells have many protective mechanisms against background levels of ionising radiation (IR) orchestrated by molecular changes in expression, post-translation modifications and subcellular localisation. Radiotherapeutic treatment in oncology attempts to overwhelm such mechanisms, but radio-resistance ...
ORGANISM(S): Homo sapiens (Human) 
2024-12-16 | PXD055123 | Pride
Lc-ms/ms Irradiation Human Subcellular fractionation A549 cells 
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