Sort   by:  
 Page size 
ProteomicsPathology tissue-quantitative mass spectrometry analysis to profile histone post-translational modification patterns in patient samples
Histone post-translational modifications (hPTMs) generate a complex combinatorial code that has been implicated with various pathologies, including cancer. Dissecting such a code in physiological and diseased states may be exploited for epigenetic biomarker discovery, but hPTM analysis in clinical s...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2016-08-25 | MSV000080100 | MassIVE
ProteomicsSpatial and temporal effects in protein post-translational modification distributions in the developing mouse brain
Protein post-translational modification (PTM) is a powerful way to modify the behavior of cellular proteins and thereby cellular behavior. Multiple recent studies of evolutionary trends have shown that certain pairs of protein post-translational modifications tend to occur closer to each other than ...
ORGANISM(S): Mus musculus (Mouse) 
2016-04-11 | PXD003932 | Pride
Development Post-translational modifications Mouse brain 
UnknownPTM-Mamba: a PTM-aware protein language model with bidirectional gated Mamba blocks.
Not available
S-EPMC12074982 | biostudies-literature
ProteomicsGlobal post-translational modification profiling of HIV-1-infected cells reveals mechanisms of host cellular pathway remodeling
Viruses must effectively remodel host cellular pathways to replicate and evade immune defenses, and they must do so with limited genomic coding capacity. Targeting post-translational modification (PTM) pathways provides a mechanism by which viruses can broadly and rapidly transform a hostile host en...
ORGANISM(S): Homo sapiens (Human) 
2022-04-14 | PXD032085 | Pride
Hiv-1 Proteomics Vif B56 Ubiquitination Vpr Pp2a Phosphorylation Histone h1 Systems biology 
ProteomicsReactive Metabolite-induced Protein Glutathionylation Mechanistically Accounts for Acetaminophen Hepatotoxicity
Although covalent protein binding is established as the pivotal event underpinning acetaminophen (APAP) toxicity, its mechanistic details remain unclear. In this study, we demonstrated that APAP induces widespread protein glutathionylation in a time-, dose- and bioactivation-dependent manner in Hepa...
ORGANISM(S): Homo Sapiens (human) 
2018-09-20 | PXD009986 | JPOST Repository
UnknowniPTMnet: Integrative Bioinformatics for Studying PTM Networks.
Not available
S-EPMC5436273 | biostudies-literature
UnknownPTM-Mamba: A PTM-Aware Protein Language Model with Bidirectional Gated Mamba Blocks.
Not available
S-EPMC10925343 | biostudies-literature
UnknownT cells specific for post-translational modifications escape intrathymic tolerance induction.
Not available
S-EPMC5783942 | biostudies-literature
GenomicsActin R256 mono-methylation is a conserved post-translational modification involved in transcription
Actin R256 mono-methylation is a conserved post-translational modification involved in transcription
PRJNA659255 | ENA
UnknownUtilizing Optimized Tools to Investigate PTM Crosstalk: Identifying Potential PTM Crosstalk of Acetylated Mitochondrial Proteins.
Not available
S-EPMC6027404 | biostudies-literature
Sort   by:  
 Page size