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UnknownTranscriptome analysis provides new insights into plants responses under phosphate starvation in association with chilling stress.
Not available
S-EPMC8751124 | biostudies-literature
ProteomicsMediator Kinase Complexes Regulates ATOH1-Dependent Intestinal Differentiation
Cyclin Dependent Kinases CDK8 and CDK19 (Mediator kinase) are regulatory components of the Mediator complex, a highly conserved complex that fine tunes transcriptional output. While Mediator kinase has been implicated in the transcriptional control of key pathways necessary for development and growt...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-10 | PXD030212 | Pride
Phosphoproetomics. cdk8 Cdk19 
ProteomicsIdentification of immunodominant ERV peptides critical for anti-metastatic immunity in a model of TNBC
The integration of immunotherapy into neoadjuvant treatment for triple negative breast cancer (TNBC) has improved outcomes in some patients. Pre-clinical investigation of immunotherapy resistance in the aggressive 4T1 TNBC model has been hampered by a lack of known tumor-specific epitopes. Using pro...
ORGANISM(S): Homo sapiens (Human) 
2026-09-21 | PXD069588 | Pride
Erv Tnbc Immunopeptidomics 
UnknownThe Prevalence of Polycystic Ovary Syndrome, Its Phenotypes and Cardio-Metabolic Features in a Community Sample of Iranian Population: Tehran Lipid and Glucose Study.
Not available
S-EPMC8920974 | biostudies-literature
ProteomicsThe self-peptide repertoire plays a critical role in transplant tolerance induction
While direct allorecognition underpins both solid organ allograft rejection and tolerance induction, the specific molecular targets of most directly-alloreactive CD8+ T cells have not been defined. In this study, we used a combination of genetically-engineered MHC I constructs, mice with a hepatocyt...
ORGANISM(S): Mus musculus (Mouse) 
2021-12-06 | PXD023015 | Pride
Immunopeptidomics Hla Transplantation 
ProteomicsThe self-peptide repertoire plays a critical role in transplant tolerance induction
While direct allorecognition underpins both solid organ allograft rejection and tolerance induction, the specific molecular targets of most directly-alloreactive CD8+ T cells have not been defined. In this study, we used a combination of genetically-engineered MHC I constructs, mice with a hepatocyt...
ORGANISM(S): Mus musculus (Mouse) 
2021-12-06 | PXD022695 | Pride
Immunopeptidomics Hla Transplantation 
UnknownA novel large germ line deletion in adenomatous polyposis coli (APC) gene associated with familial adenomatous polyposis.
Not available
S-EPMC6305644 | biostudies-literature
ProteomicsCirculating HLA Ligandomes Reflect Tumour Antigen Landscapes in Melanoma
Melanoma is a highly immunogenic malignancy in which T cell recognition of HLA-presented peptides plays a central role in tumour control. While immunopeptidomics has enabled detailed characterisation of melanoma antigen repertoires, its clinical application is limited by restricted access to tumour ...
ORGANISM(S): Homo sapiens (Human) 
2026-10-29 | PXD078553 | Pride
Soluble hla Melanoma Immunopeptidomics Biopsy Biomarkers 
ProteomicsEwing sarcoma immunopeptidomics
Ewing Sarcoma (EwS) is a rare pediatric malignancy characterized by a unique t(11:22) (q24;q12) translocation resulting in the EWSR1::FLI1 fusion. Recent reports indicate the EWSR1::FLI1 fusion onco-protein drives aberrant expression of numerous transcripts, including Lipoxygenase Homology Domains 1...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD046803 | Pride
Ewing sarcoma Ifn gamma Proteomics Immunopeptidomics 
ProteomicsDimethyl Sulfoxide Enhances HLA Peptide Identification
Immunopeptidomics relies on LC-MS/MS for comprehensive profiling of HLA-bound peptides, yet detection remains challenging due to their non-tryptic nature, variable lengths, and lack of basic residues, which limit ionisation and fragmentation efficiency. To address these limitations, we investigated ...
ORGANISM(S): Homo sapiens (Human) 
2026-03-30 | PXD072997 | Pride
Immunopeptidomics Dmso Supercharging 
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