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TranscriptomicsTranscription profiling of mouse nephron to assess circadian rhythms
Renal excretion of water and major electrolytes exhibits a significant circadian rhythm. This functional periodicity is believed to result, at least in part, from circadian changes in secretion/reabsorption capacities of the distal nephron and collecting ducts. Here, we studied the molecular mechani...
ORGANISM(S): Mus musculus 
2009-10-30 | E-GEOD-17739 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis thaliana phytochrome interacting factors 4 and 5 redundantly limit seedling de-etiolation in continuous far-red light.
Phytochromes are red/far red photosensors regulating numerous developmental programs in plants. Among them phytochrome A (phyA) is essential to enable seedling de-etiolation in continuous far-red (FR) light a condition mimicking the environment under a dense canopy. The ecological relevance of this ...
ORGANISM(S): Arabidopsis thaliana 
2009-09-17 | E-GEOD-16333 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse PPAR-apha knockouts reveals gender-specific gene repression of PPAR-alpha knockouts in liver and heart
Most metabolic studies are conducted in male animals; thus, the molecular mechanism controlling gender-specific pathways has been neglected, including sex-dependent responses to peroxisome proliferator-activated receptors (PPARs). Here we show that PPARalpha has broad female-dependent repressive act...
ORGANISM(S): Mus musculus 
2009-11-16 | E-GEOD-14395 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse pressure overload induced cardiomyopathy time series
Expression profiles at various time points after surgical intervention for pressure-overload induced cardiac hypertrophy and failure.
ORGANISM(S): Mus musculus 
2004-06-30 | E-MEXP-105 | biostudies-arrayexpress
UnknownIdentification of signaling components required for the prediction of cytokine release in RAW 264.7 macrophages.
Not available
S-EPMC1431720 | biostudies-literature
TranscriptomicsImpact of normalization on Agilent miRNA microarray expression profiling
Profiling miRNA levels in cells with miRNA-microarrays is becoming a widely used technique. Although normalization methods for mRNA gene expression arrays are well established, miRNA array normalization has so far not been investigated in detail. In this study we investigate the impact of normalizat...
ORGANISM(S): Homo sapiens 
2009-02-16 | E-GEOD-12085 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of mouse tissues from different mouse strains to investigate the effects of copy number variation on gene expression
Copy number variation (CNV) of DNA segments has recently been identified as a major source of genetic diversity, but a more comprehensive understanding of the extent and phenotypic effect of this type of variation is only beginning to emerge. In this study we generated genome-wide expression data fr...
ORGANISM(S): Mus musculus 
2009-02-28 | E-GEOD-10744 | biostudies-arrayexpress
TranscriptomicsIdentification and functional characterization of Rca1, a transcription factor involved in both antifungal susceptibility and host response in Candida albicans
The identification of novel transcription factors associated to antifungal response may allow the discovery of fungal specific targets for new therapeutic strategies. A collection of 241 C. albicans transcriptional regulators mutants was screened for altered susceptibility to fluconazole, caspofungi...
ORGANISM(S): Candida albicans 
2012-05-02 | E-GEOD-37682 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse pressure overload induced cardiomyopathy in gp130 knock-out mice
Comparison between wild-type and cardiomyocyte-restricted knock-out of IL6 cytokines receptor component gp130 after surgical intervention for pressure-overload induced cardiomyopathy.
ORGANISM(S): Mus musculus 
2004-06-30 | E-MEXP-104 | biostudies-arrayexpress
TranscriptomicsDifferential virulence gene expression in the pathogenic dermatophyte Arthroderma benhamiae in vitro versus infection
Although dermatophytes are the most common agents of superficial mycoses in humans and animals, the molecular basis of the pathogenicity of these fungi is largely unknown. In vitro digestion of keratin by dermatophytes is associated with the secretion of multiple proteases, which are assumed to be r...
ORGANISM(S): Arthroderma benhamiae 
2010-03-04 | E-GEOD-15873 | biostudies-arrayexpress
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