Sort   by:  
 Page size 
Long non-coding RNAs (lncRNAs) play critical regulatory roles in primate-specific biological processes, yet many primate-specific lncRNAs and their protein interactors remain poorly characterized. In this study, we focused on primate-specific lncRNAs as potential drivers of protein interactions. Usi...
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD075354 | Pride
Only a minuscule fraction of long non-coding RNAs (lncRNAs) are well characterized. The evolutionary history of lncRNAs can provide insights into their functionality, but comparative analyses have been precluded by our ignorance of lncRNAs in non-model organisms. Here, we use RNA sequencing to ident...
ORGANISM(S): Ornithorhynchus anatinus 
Evolution of an lncRNA leads to a primate specific modulation of alternative splicing
LncRNA CHROMR regulates antiviral immunity in humans [ChIRP-Seq]
Long non-coding RNAs (lncRNAs) are important regulators of the immune response. Here we identify a novel function for the primate-specific lncRNA, CHROMR. We established that CHROME is most highly transcribed in human macrophages treated with influenza virus and/or polyIC.
ORGANISM(S): Homo sapiens 
2022-08-23 | GSE198808 | GEO
Long non-coding RNAs (lncRNAs) are important regulators of the immune response. Here we identify a novel function for the primate-specific lncRNA, CHROME. We established that CHROME is most highly transcribed in human macrophages treated with influenza virus and/or polyIC.
ORGANISM(S): Homo sapiens 
2022-08-23 | GSE191238 | GEO
LncRNA CHROME regulates the interferon response to viral challenge [COVID]
Long non-coding RNAs (lncRNAs) are important regulators of the immune response. Here we identify a novel function for the primate-specific lncRNA, CHROME. We established that CHROME is most highly transcribed in human macrophages treated with bacterial lipopolysaccharide and RNA viruses.
ORGANISM(S): Homo sapiens 
2022-08-23 | GSE190412 | GEO
Sort   by:  
 Page size