Programmed dna elimination

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CHEBI ID

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Classification

helminths (6)

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Transcription profiling by array (27)
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Lab affiliation

Institute of Cell Biology, University of Bern, Bern 3012, Switzerland (1)
Institute of Cell Biology, University of Bern, Bern, Switzerland (1)
Laboratory of Non-coding RNA and Genome Rearrangements, Institute of Biochemistry and Biophysics, PAS (1)
Laboratory of Non-coding RNA and Genome Rearrangements, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland (1)
NUS Singapore (1)
Protein Analysis Unit ZfP BioMedical Center, LMU Munich Grosshaderner Strasse 9 82152 Planegg-Martinsried Tel. +49 89 2180 75420 (1)
Université Paris Cité, CNRS, Institut Jacques Monod, F-75013 PARIS, FRANCE (1)
Université Paris Cité, CNRS, Institut Jacques Monod, F-75013 Paris, France (1)
Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), 91198, Gif-sur-Yvette, France (1)

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A developmental condensin I complex assists the Paramecium PiggyMac domesticated transposase during programmed DNA elimination

Prokaryotes and eukaryotes use diverse strategies to cope with invading mobile genetic elements, including programmed DNA elimination (PDE). In the ciliate Paramecium, elimination of transposable elements and their relics requires the PiggyMac (Pgm) endonuclease and its five PgmL partners, yet how t...

ORGANISM(S): Paramecium tetraurelia

2026-04-01 | PXD068119 | Pride

Biased transcription and selective degradation of small RNAs shape the pattern of DNA elimination in Tetrahymena

The ciliated protozoan Tetrahymena undergoes extensive programmed DNA elimination when the germline micronucleus produces the new macronucleus during sexual reproduction. DNA elimination is epigenetically controlled by DNA sequences of the parental macronuclear genome, and this epigenetic regulation...

ORGANISM(S): Tetrahymena thermophila

2012-06-21 | E-GEOD-38768 | biostudies-arrayexpress

CENP-A Deposition Defines Sequences for Retention and Elimination during Programmed DNA Elimination in Nematode

Organisms invest significant effort into maintaining genome stability. However, in diverse groups of eukaryotes, portions or entire chromosomes are lost in early development or during sex determination, a process known as programmed DNA elimination. Little is known about how different segments of t...

ORGANISM(S): Ascaris suum

2016-07-15 | E-GEOD-76914 | biostudies-arrayexpress

Linking Germline Telomere Removal to Global Programmed DNA Elimination in Tetrahymena Genome Differentiation

Linking Germline Telomere Removal to Global Programmed DNA Elimination in Tetrahymena

PRJEB112135 | ENA

A histone methyltransferase-independent function of PRC2 controls small RNA dynamics during programmed DNA elimination in Paramecium

To limit transposable element (TE) mobilization, most eukaryotes have evolved small RNAs to silence TE activity via homology-dependent mechanisms. Small RNAs, 20-30 nucleotides in length, bind to PIWI proteins and guide them to nascent transcripts by sequence complementarity, triggering the recruitm...

ORGANISM(S): Paramecium tetraurelia

2025-09-22 | PXD063336 | Pride

Histone methyltransferase Programmed dna elimination Prc2 Small rna Paramecium

DNA elimination in Mesorhabditis_1

First description of Programmed-DNA Elimination in M. belari and M. spiculigera

PRJEB59059 | ENA

Condensin I enables programmed DNA elimination in Paramecium

A developmental condensin I complex assists the Paramecium PiggyMac domesticated transposase during programmed DNA elimination

PRJEB96275 | ENA

Silencing of Germline-Expressed Genes by DNA Elimination in Somatic Cells

Chromatin diminution is the programmed elimination of specific DNA sequences during development. It occurs in diverse species, but the function(s) of diminution and the specificity of sequence loss remain largely unknown. Diminution in the nematode Ascaris suum occurs during early embryonic cleavage...

ORGANISM(S): Ascaris suum

2012-11-13 | E-GEOD-38470 | biostudies-arrayexpress

Spatial genome organization is associated with nematode programmed DNA elimination

PRJNA1392313 | ENA

Cytosine methylation and hydroxymethylation mark DNA for elimination in Oxytricha trifallax.

We report the existence of both methylcytosine and hydroxymethylcytosine in the genomic DNA of the ciliate Oxytricha trifallax during its genome rearrangement process. These modifications are dynamically added, de novo, to sequences targeted for elimination and are not present after the rearrangemen...

ORGANISM(S): Oxytricha trifallax

2012-09-26 | E-GEOD-41060 | biostudies-arrayexpress

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