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ProteomicsHuman WIPI interactome (LC-MSMS)
Analysis of the WIPI protein interactome using nanoLC-MS/MS analysis upon the immunopurification of GFP-tagged WIPI1, WIPI2B, WIPI2D, WIPI3, WIPI4 and GFP alone from U2OS cells. Prior to immunopurifications, cells were either kept under fed (DMEM/FCS) or starved conditions (EBSS), or were treated wi...
ORGANISM(S): Homo sapiens (Human) 
2017-06-01 | PXD006119 | Pride
Wipi2 Lc-msms Autophagy Wipi1 Wipi4 Wipi3 
ProteomicsSILAC phosphoproteome analysis upon transient Abl1/2 or DDR1 knockdown in human U-2 OS cells
Analysis of changes in the phosphoproteome upon transient siRNA-mediated knockdown of ABL1/ABL2 or DDR1 for 48 hours. CILAC phosphoproteome analysis was conducted after 48hrs using human U-2 OS cells.
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD023146 | Pride
Abl2 Silac Abl1 Ddr1 
TranscriptomicsCP001: Modulation of glutamine metabolism by the PI3K-PKB/c-akt-FOXO network regulates autophagy
The PI3K-PKB/c-akt-FOXO signalling network provides a major intracellular hub for regulation of cell proliferation, survival and stress resistance1. Here we report a novel function for FOXO transcription factors in regulating autophagy through modulation of intracellular glutamine levels. To identif...
ORGANISM(S): Mus musculus 
2012-07-21 | E-GEOD-35701 | biostudies-arrayexpress
TranscriptomicsCP003: Modulation of glutamine metabolism by the PI3K-PKB/c-akt-FOXO network regulates autophagy
The PI3K-PKB/c-akt-FOXO signalling network provides a major intracellular hub for regulation of cell proliferation, survival and stress resistance1. Here we report a novel function for FOXO transcription factors in regulating autophagy through modulation of intracellular glutamine levels. To identif...
ORGANISM(S): Mus musculus 
2012-07-21 | E-GEOD-35703 | biostudies-arrayexpress
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