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Small molecules not only represent cellular building blocks and metabolic intermediates, but also regulatory ligands and signaling molecules that interact with proteins. Although these interactions affect cellular metabolism, growth, and development, they have been largely understudied. Herein, we d...
2018-07-19 | MTBLS94 | MetaboLights
Unbiased proteomic analysis of plasma samples holds the promise to reveal clinically invaluable disease biomarkers. However the tremendous dynamic range of the plasma proteome has so far hampered the identification of such low abundant markers. To overcome this challenge we analyzed the plasma micro...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080835 | MassIVE
Unbiased proteomic analysis of plasma samples holds the promise to reveal clinically invaluable disease biomarkers. However the tremendous dynamic range of the plasma proteome has so far hampered the identification of such low abundant markers. To overcome this challenge we analyzed the plasma micro...
ORGANISM(S): Homo sapiens (Human) 
2015-01-28 | PXD001194 | Pride
Protein–metabolite interactions (PMIs) are critical regulators of cellular processes, yet their roles in plant–pathogen interactions remain poorly understood. Here, we applied PROMIS (Protein–Metabolite Interactions using Size separation) to map the Arabidopsis interactome during infection with Pseu...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) Pseudomonas syringae pv. tomato str. DC3000 Bacteria 
2026-05-05 | PXD069625 | Pride
PROMIS T2D-GENES Exome Sequencing Study
PROMIS T2D-GENES Exome Sequencing Study
Herein, we describe a method, dubbed PROMIS that allows simultaneous, global analysis of endogenous protein–small-molecule and protein-protein complexes. To this end a cell-free native lysate was subjected to size-exclusion chromatography followed by quantitative metabolomic and proteomic analysis. ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2018-06-06 | PXD009714 | Pride
NHLBI TOPMed - Centers for Common Disease Genomics (CCDG): Pakistan Risk of Myocardial Infarction Study (PROMIS)
NHLBI TOPMed - Centers for Common Disease Genomics (CCDG): Pakistan Risk of Myocardial Infarction Study (PROMIS)
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