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Toxoplasma gondii is a ubiquitous apicomplexan protozoan parasite that can infect all warm-blooded animals and lead to toxoplasmosis. Discovering efficient methods for diagnosing T. gondii infection and developing vaccine candidates are essential for controlling this disease. Circulating antigens (C...
ORGANISM(S): Toxoplasma gondii RH 
2021-01-04 | PXD021938 | Pride
Protective heterologous T cell immunity in COVID-19 induced by MMR and Tdap vaccine antigens
Edema factor of anthrax binds to the protective antigen (PA83) which cleaves to PA63 and PA20. The role of PA20 was examined using highthroughput gene expression analysis of human peripheral blood mononuclear cells (PBMC) exposed to PA20. Keywords: Toxicity determination PBMC obtained from differe...
ORGANISM(S): Homo sapiens 
Pseudomonas aeruginosa is an opportunistic Gram negative pathogen that causes severe nosocomial infections in susceptible individuals due to the emergence of multi-drug resistant strains. There are no approved vaccines against P. aeruginosa infections nor candidates in active clinical development, h...
ORGANISM(S): Pseudomonas aeruginosa PA14 Bacteria 
2025-05-07 | PXD055823 | Pride
The immune response against tuberculosis relies, at least in part, on CD4+ T cells. Protective vaccines require the induction of antigen-specific CD4+ T cells via mycobacterial peptides presented by MHC class-II in infected macrophages. We have purified MHC class-I and MHC-II peptides and analysed t...
ORGANISM(S): Mycobacterium tuberculosis variant bovis BCG 
Immunomic screening of mice immune sera with different protection efficiencies against the whole P. yoelii 17X parasite proteome was performed to identify the repertoire of antigens recognized by those sera. The calculation of weighted scores reflecting the likelihood of protection of each antigens ...
ORGANISM(S): Plasmodium yoelii 17X 
2019-02-15 | PXD010567 | Pride
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