Sort   by:  
 Page size 
MetabolomicsTranscript, protein and metabolite temporal dynamics in the CAM plant Agave
Already a proven mechanism for drought sustainability, crassulacean acid metabolism (CAM) is a specialized type of photosynthesis that maximizes water-use efficiency (WUE) via an inverse (compared to C3 and C4 photosynthesis-performing species) day/night pattern of stomatal closure/opening to shift ...
2017-10-13 | MTBLS363 | MetaboLights
MetabolomicsUnveiling superior phenol detoxification and degradation ability in Candida tropicalis SHC-03: A comparative study with Saccharomyces cerevisiae BY4742

This study examined the phenol degradation capabilities and oxidative stress responses of Candida tropicalis SHC-03, demonstrating its metabolic superiority and resilience compared to Saccharomyces cerevisiae BY4742 in a culture medium with phenol as the sole carbon source. Through comparative gr...

2024-10-04 | MTBLS10757 | MetaboLights
MetabolomicsMechanisms of poly(butylene adipate-co-terephthalate) microplastic degradation in agricultural soil: Insights from the soybean rhizosphere

The increasing application of biodegradable mulch films in agriculture has raised concerns regarding the potential persistence of biodegradable microplastics (BMPs) in soil and their subsequent ecological impacts. Although these materials are designed to mineralize, their actual rates of breakdow...

2026-01-07 | MTBLS12524 | MetaboLights
ProteomicsChanges in Protein Turn-over Rates Regulate Tryptophan and Glucosinolate Biosynthesis, IAA Transport and Photosynthesis in Arabidopsis Growth and Defense Transitions
Changes in protein synthesis and degradation rates, transcript, protein and phytohormone abundance of 99 targets using qPCR and LC-MS parallel reaction monitoring (PRM) were measured in the transitions between optimal growth conditions (homeostasis), fully induced pattern triggered immunity (PTI) an...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2023-10-13 | PXD041215 | Pride
Translational regulation Photosynthesis Protein degradation rates Pti Glucosinolates Myc2 Phytohormone Proteomics Protein synthesis rates Auxin Pin proteins 
MetabolomicsThe Impact of Ethnicity and Intra-Pancreatic Fat on the Postprandial Metabolome Response to Whey Protein in Overweight Asian Chinese and European Caucasian Women with Prediabetes
The 'Thin on the Outside Fat on the Inside' TOFI_Asia study found Asian Chinese to be more susceptible to Type 2 Diabetes (T2D) compared to European Caucasians matched for gender and body mass index (BMI). This was influenced by degree of visceral adipose deposition and ectopic fat accumulation in k...
2022-10-12 | MTBLS5568 | MetaboLights
TranscriptomicsRNA degradation in proliferating and differentiated C2C12 muscle precursor cells analyzed on Affymetrix exon arrays
Steady-state RNA levels are a result of RNA synthesis and degradation. The importance of transcription-factor mediated induction or repression of mRNA synthesis is well established, but the role and mechanisms of RNA degradation are less well understood. We globally evaluated the RNA decay rates in ...
ORGANISM(S): Mus musculus 
2010-09-22 | E-GEOD-14387 | biostudies-arrayexpress
TranscriptomicsGlobal analysis of mRNA degradation reveals Xrn1-dependent buffering of transcript levels
The rates of mRNA synthesis and degradation determine cellular mRNA levels and can be monitored by comparative Dynamic Transcriptome Analysis (cDTA) that uses non-perturbing metabolic RNA labeling. Here we present cDTA data for 46 yeast strains lacking genes involved in mRNA degradation and metaboli...
ORGANISM(S): Schizosaccharomyces pombe 
2013-10-18 | E-MTAB-1525 | biostudies-arrayexpress
ProteomicsGlobal analysis of protein degradation rates during prion infection
Prion diseases are rare, neurological disorders caused by the misfolding of the cellular prion protein (PrPC). The misfolded conformers aggregate into cytotoxic fibrils (PrPSc) that facilitate the conversion of additional prion proteins into their misfolded form. Intracellular PrPSc aggregates prima...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-08 | PXD014577 | Pride
N2a Lysosome Cell culture Prion Rml 
ProteomicsGlobal analysis of protein degradation rates in wildtype, Atg5-/- and Atg7-/- primary human fibroblasts
In this project, we employed a dynamic mass spectrometry-based proteomic approach to obtain global maps of basal autophagic flux in human primary fibroblasts (HCA2-hTert). The data provide a comparison of protein degradation rates between wildtype and autophagy deficient (Atg5-/- and Atg7-/-) cells....
ORGANISM(S): Homo sapiens (Human) 
2016-06-14 | PXD003562 | Pride
Human primary fibroblasts Atg7 Autophagy Atg5 Protein degradation rates 
ProteomicsGlobal up-regulation of protein degradation in quiescent cells
In this project, we employed a dynamic mass spectrometry-based proteomic approach to obtain global maps of basal autophagic flux in human primary fibroblasts (HCA2-hTert). The data provide a comparison of protein degradation rates between dividing and quiescent HCA2-hTert cells. To further investiga...
ORGANISM(S): Homo sapiens (Human) 
2017-11-01 | PXD004937 | Pride
Quiescence Autophagy Human primary cells Dividing Dynamic silac Proteasome Protein degradation rates Silac Psme1 
Sort   by:  
 Page size