Sort   by:  
 Page size 
ProteomicsPSD-95 interactome in presence and absence of Xph20 intrabody
In the context of intrabodies development for the synaptic protein PSD-95, we use proteomic approaches to evaluate the possible impact of one of our evolved PSD-95 binders on the endogenous PSD-95 function. More precisely, we compare the interactome of PSD-95 in presence or absence of the Xph20 bind...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-01-26 | PXD045002 | Pride
Intrabody Synapse Psd-95 
GenomicsAmycolatopsis sp. PSD-21
Amycolatopsis sp. PSD-21 Genome sequencing
PRJNA1426182 | ENA
TranscriptomicsSaccharomyces cerevisiae transcriptome analysis of conditional yjr141w-psd mutant compared to control strain
The experiment investigates the consequences of Yjr141w downregulation on gene expression in yeast. The essential protein Yjr141w was depleted from cells using a tagged variant (Yjr141w-psd). The photo-sensitive degron (psd) module initiates degradation of the tag and its associated protein upon blu...
ORGANISM(S): Saccharomyces cerevisiae 
2018-03-18 | E-MTAB-5022 | biostudies-arrayexpress
ProteomicsMS analysis of photocrosslink adducts for the mapping of interaction sites of selective engineered PSD-95 PDZ domain ligands
Designing highly specific modulators of protein-protein interactions (PPIs) is especially challenging in the context of multiple paralogs and conserved interaction surfaces. In this case, direct generation of selective and competitive inhibitors is hindered by high similarity within the evolutionary...
ORGANISM(S): Rattus norvegicus (Rat) 
2019-11-12 | PXD015366 | Pride
Engineered ligand/pdz domains/photocrosslinking/p-azidophenylalanine 
TranscriptomicsTranscription profiling of mouse SAP102 and PSD-95 knockouts compared to their wild-type littermates
Effect of ablation of SAP102 or PSD-95 genes in mice compared to wild-types littermates
ORGANISM(S): Mus musculus 
2007-09-01 | E-MEXP-1159 | biostudies-arrayexpress
GenomicsTargeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
PRJNA914766 | ENA
GenomicsTargeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment [2]
Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment [2]
PRJNA1055532 | ENA
ProteomicsDevelopmental profile of core postsynaptic density protein complexes integrates signaling components of brain disorders
The postsynaptic density (PSD) contains a collection of scaffold proteins used for the assembly of synaptic signaling complexes and disruption of this signaling machinery might be implicated in a variety of brain disorders. However, it is not known how the core-scaffold machinery associates this col...
ORGANISM(S): Mus musculus (Mouse) 
2017-08-22 | PXD006277 | Pride
Neuron Synaptic Psd 
ProteomicsComponents of lean-type and enriched-type PSD lattices
This project proposes a postsynaptic density (PSD) lattice model comprising a non-microtubule tubulin-based backbone structure and its associated proteins, including various PSD scaffold/adaptor proteins and other PSD proteins.
ORGANISM(S): Cellular Organisms 
2021-05-08 | PXD024712 | JPOST Repository
ProteomicsIn-depth protein profiling of mouse hippocampal postsynaptic density using data-independent acquisition proteomics
In the present study, we catalogued the proteome of postsynaptic density (PSD) derived from the hippocampus of three-week old (P19) mice. samples in 100 min gradient time.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2019-08-27 | MSV000084240 | MassIVE
Sort   by:  
 Page size