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The aim of this work was to characterize proteome of aqueous humor from subjects with various eye conditions such as cataract, glaucoma and pseudoexfoliation syndrome by high-resolution chromate-mass-spectrometry. Twenty nine human aqueous humor samples were processed by shotgun proteomics. Data was...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080838 | MassIVE
The aim of this work was to characterize proteome of aqueous humor from subjects with various eye conditions such as cataract, glaucoma and pseudoexfoliation syndrome by high-resolution chromate-mass-spectrometry. Twenty nine human aqueous humor samples were processed by shotgun proteomics. Data was...
ORGANISM(S): Homo sapiens (Human) 
2016-05-23 | PXD002623 | Pride
We provided a comprehensive plasma proteome analysis and expanded the profile of human plasma proteome. The differential plasma proteomic analysis of age-related cataract and exfoliation syndrome with/without glaucoma indicated that plasma proteome can reflect the pathophysiological situation of dis...
ORGANISM(S): Homo Sapiens 
2025-03-17 | PXD061945 |
In this study 3 pooling experiments were performed. In each of the 3 cohorts, a 'case' and a 'control' blood pool was compared - the goal being to identify single nucleotide polymorphisms with significantly different estimated pooling allele frequencies between cases and controls. For cohort 1, 100 ...
ORGANISM(S): Homo sapiens 
RNAseq of Lens Capsular Epithelium in Pseudoexfoliation Syndrome
Pseudoexfoliation syndrome (PEXS) is a late-onset disorder in which fibrillar material accumulates at abnormally high concentrations mainly in the anterior segment of the eye. PEXS is the most common cause of secondary glaucoma, which can ultimately lead to blindness and is associated with a higher ...
ORGANISM(S): Homo sapiens 
2018-01-31 | GSE93205 | GEO
The goal of this study was to identify functional variants that play a role in exfoliation syndrome (XFS) pathogenesis. We sequenced the entire LOXL1 locus in 50 South African XFS cases and 50 matched controls. The most strongly associated variants in this dataset were found in a ~7kb region spannin...
ORGANISM(S): Homo sapiens 
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