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GenomicsP2X4 Purinergic Receptor Loss Alters Macrophage Homeostasis, Cytokine Secretion, and Phagocytosis in a Myeloid-Specific P2X4 Purinergic Receptor Knockout Mouse.
P2X4 Purinergic Receptor Loss Alters Macrophage Homeostasis, Cytokine Secretion, and Phagocytosis in a Myeloid-Specific P2X4 Purinergic Receptor Knockout Mouse.
PRJNA1524247 | ENA
UnknownP2 purinergic receptor dysregulation in urologic disease.
Not available
S-EPMC9184359 | biostudies-literature
TranscriptomicsP2X4 Purinergic Receptor Loss Alters Macrophage Homeostasis, Cytokine Secretion, and Phagocytosis in a Myeloid-Specific P2X4 Purinergic Receptor Knockout Mouse.
Introduction: The P2X4 purinergic receptor is robustly expressed on tumor-associated macrophages; however, the role of P2X4 purinergic receptors on macrophages is not fully defined. To investigate the functional role of P2X4 purinergic receptor in macrophages, we generated and characterized a myeloi...
ORGANISM(S): Mus musculus 
2026-09-09 | GSE346257 | GEO
GenomicsExpressing data from endothelial cells overexpressing the purinergic receptor P2Y2
Expressing data from endothelial cells overexpressing the purinergic receptor P2Y2
PRJNA552557 | ENA
TranscriptomicsGene expression profiling of GPR86 (P2RY13) KO mice
The purinergic receptor P2Y13 (P2RY13) has been shown to play a role in the uptake of holo-HDL particles in in vitro hepatocyte experiments. In order to determine the role of P2Y13 in lipoprotein metabolism in vivo, we ablated the expression of this gene in mice and found that P2Y13 knockout mice ha...
ORGANISM(S): Mus musculus 
2010-09-10 | E-GEOD-20920 | biostudies-arrayexpress
TranscriptomicsGene Expression Profile in thyroid of Transgenic Mice over-expressing the Adenosine Receptor 2a
Mutations of the thyrotropin receptor leading to constitutive activation of the cAMP cascade are responsible for the development of hot nodules, if arising in a somatic cell, and non-auto-immune hyperthyroidism, when occurring in a germinal cell. An animal model of constitutive activation of the thy...
ORGANISM(S): Mus musculus 
2010-06-05 | E-GEOD-780 | biostudies-arrayexpress
UnknownThe impact of commercially available purinergic ligands on purinergic signalling research.
Not available
S-EPMC3265706 | biostudies-literature
ProteomicsBlocking microglial reactivity via purinergic receptors prevents subacute cognitive deficits after TIA
Our research presents a new animal model of transient ischemic attack (TIA) that mimics brief episodes without cell loss, but results in neuronal and behavioral deficits. We identified excessive microglial reactivity, driven by acute ATP release, as a key factor in post-TIA neurological deficits, wh...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-24 | PXD070754 | Pride
Synapse Tia Microglia Purinergic receptor Atp 
UnknownCardiomyogenesis of embryonic stem cells upon purinergic receptor activation by ADP and ATP.
Not available
S-EPMC4648792 | biostudies-literature
UnknownAltered Purinergic Signaling in Neurodevelopmental Disorders: Focus on P2 Receptors.
Not available
S-EPMC10216121 | biostudies-literature
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