Sort   by:  
 Page size 
MetabolomicsLive Combined Bifidobacterium Attenuates Rivaroxaban-Associated Colonic Bleeding in Mice: Evidence for a Substantial Gut Microbiota-Dependent Component
This study investigated fecal metabolic alterations associated with live combined Bifidobacterium (LCB) treatment in a mouse model of rivaroxaban-associated colonic bleeding. Male C57BL/6J mice were included in two experiments comprising normal control, rivaroxaban-treated, rivaroxaban followed by L...
2026-10-09 | MTBLS15531 | MetaboLights
MetabolomicsMulti-Omics Unveils Strain-Specific Neuroactive Metabolite Production Linked to Inflammation Modulation by Bacteroides and Their Vesicles

18 Bacteroidetes isoaltes were analyzed for their neuroactive potentail using un-targeted and targeted metabolomics. The bacteria were grown to stationary phase, the supernatant was separated and purified using 0.22 um filter. The metabolome from the supernatant was extracted using standard Metha...

2025-08-12 | MTBLS10526 | MetaboLights
MetabolomicsComprehensive lipid analysis of green Arabica coffee beans by LC-HRMS/MS
Lipids play an important role in coffee bean development, coffee brew and in the effects of coffee on human health. They account for around 17% of the dry bean weight and encompass different classes and subclasses, mostly triacylglycerols (TAG) and a minor quantity of phospholipids (PL) and βN-alkan...
2021-11-19 | MTBLS1972 | MetaboLights
MetabolomicsSpatial metabolomics of in situ, host-microbe interactions (UPLC-MS/MS assay)
Spatial metabolomics describes the location and chemistry of small molecules involved in metabolic phenotypes, defense molecules and chemical interactions in natural communities. Most current techniques are unable to spatially link the genotype and metabolic phenotype of microorganisms in situ at a ...
2019-11-15 | MTBLS746 | MetaboLights
ProteomicsProteomic Analysis of rattus norvegicus colonic mucosa following acupuncture treatment for irritable bowel syndrome with diarrhea by label-free LC–MS/MS
To investigate the molecular pathological mechanisms of irritable bowel syndrome with diarrhea (IBS-D) and elucidate the effects of acupuncture on IBS-D colonic mucosa protein abundance in rats, a label-free high-throughput liquid chromatography-tandem mass spectrometry (LC-MS)-based proteomics anal...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-10-14 | PXD025558 | Pride
Lc-msms Colonic mucosa Rat Acupuncture 
MetabolomicsWalnut protein hydrolysate alleviates neuroinflammation and memory impairment in naturally aged mice via a gut microbiota-metabolite-neuroinflammation axis
This study investigated age-associated alterations in the serum metabolome and the metabolic effects of walnut protein hydrolysate (WPH) supplementation in naturally aged mice. Male C57BL/6J mice at different ages (2-month, 10-month and 18-month) were used to characterize metabolic changes associate...
2026-09-04 | MTBLS15363 | MetaboLights
ProteomicsData on proteome of Mycoplasma hominis cultivated with arginine or thymidine as a carbon source
M. hominis cells were grown in liquid medium supplied with arginine or thymidine as a carbon source. LC-MS analysis was performed on Ultimate 3000 Nano LC System (Thermo Fisher Scientific) coupled with Q Exactive HF benchtop Orbitrap mass spectrometer (Thermo Fisher Scientific) via a nanoelectrospra...
ORGANISM(S): Mycoplasma hominis ATCC 23114 
2020-05-06 | PXD018714 | Pride
Growth conditions Hominis Proteome Mycoplasma 
MetabolomicsGut Microbiota-Derived Indole-3-Propionic Acid Ameliorates Diabetic Cardiomyopathy by Regulating Mitochondrial Dynamics via the AhR/Nrf2 Pathway
This study investigated serum metabolic alterations in a mouse model of diabetic cardiomyopathy and evaluated the protective role of the gut microbiota-derived metabolite indole-3-propionic acid. Serum samples from mice were analyzed using untargeted LC-MS metabolomics. The study focused on the rela...
2026-07-26 | MTBLS14953 | MetaboLights
ProteomicsOn the characterisation of the porcine gland-specific salivary proteome using MALDI-TOF/TOF MS and Q-Exactive orbitrap MS/MS
To expand the knowledge on the porcine salivary proteome, secretions from the three major salivary glands were collected from anaesthetised piglets. Pilocarpine and isoproterenol were simultaneously injected intraperitoneally to increase the volume and protein concentration of the saliva, respective...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2019-02-15 | PXD008853 | Pride
Salivary proteome Lc-ms Itraq Gland-specific saliva Pig 
MetabolomicsUntargeted Plasma Metabolomic Profiling of Parkinson’s Disease
Untargeted LC–MS metabolomic profiling was performed on plasma samples from a discovery cohort comprising 50 patients with Parkinson’s disease and 50 healthy controls. The study aimed to characterize disease-associated metabolic alterations, identify dysregulated metabolic pathways, and investigate ...
2026-09-03 | MTBLS15433 | MetaboLights
Sort   by:  
 Page size