Qi Xiaopeng X - OmicsDI

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Transcriptomics (3)
Proteomics (3)

Organisms

Mus musculus (3)
Anthoceros agrestis (2)
Helicobacter cinaedi CCUG 18818 = ATCC BAA-847 (2)
Bdellovibrio bacteriovorus (2)
Mycobacterium avium subsp. paratuberculosis (2)
Dionaea muscipula (2)
Orthomyxoviridae (2)
Panine betaherpesvirus 2 (2)
Pongo sp. (2)
recombinant SARS coronavirus (2)
Shinisaurus crocodilurus (2)
Corucia (2)
Papio hamadryas adenovirus 1 (2)
Heloderma horridum horridum (2)
Phytophthora sojae strain P6497 (2)
HIV-1 vector pNL4-3 (2)
Serpentes sp. WLS21042014 (2)
Clostridium cellulovorans 743B (2)
Streptococcus pyogenes MGAS5005 (2)
Lota lota (2)
Japanese encephalitis virus (2)
NEWT:1423687 (2)
Methanococcus maripaludis S2 (2)
Bacillus licheniformis (2)
Campylobacter jejuni subsp. jejuni 81-176 (2)
Saccharolobus islandicus (2)
Sodalinema sp. PMC 1182.19 (2)
Nodosilinea sp. ATA3-4Q-CV33 (2)
Mycobacterium avium subsp. paratuberculosis ATCC 19698 (2)
Youcai mosaic virus (1)

Repository

biostudies-arrayexpress (3)
pride (2)
iProX (1)

Tissue

Bone marrow (2)
Cell suspension culture (2)
Macrophage (2)

Disease

Primary immunodeficiency disease (2)

Technology Type

Bottom-up proteomics (2)
Mass Spectrometry (2)

Publication Date

2026 (2)
2016 (1)
2013 (1)
2009 (1)
2024 (1)

Study type

Transcription profiling by array (2)
RNA-seq of non coding RNA (1)

Release Date

2016 (1)
2013 (1)
2009 (1)

Lab affiliation

Key Laboratory for Experimental Teratology of the Ministry of Education, Advanced Medical Research Institute, Qilu Hospital, Cheeloo College of Medicine, Shandong University (2)

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Identification of ASC-interacting proteins

To explore the spatiotemporal regulation of ASC speck formation and inflammasome activation, we infected primary WT and Asc–/– bone marrow-derived macrophages (BMDMs) with the bacterium Francisella novicida to induce AIM2 inflammasome activation and then performed ASC IP-MS to identify proteins that...

ORGANISM(S): Mus musculus (Mouse)

2024-05-29 | PXD052497 | Pride

Identification of ASC-interacting proteins

To explore the spatiotemporal regulation of ASC speck formation and inflammasome activation, we treated primary WT and Asc–/– bone marrow-derived macrophages (BMDMs) with LPS (500 ng/ml) and ATP (5 mM) to activate NLRP3 inflammasome activation and then performed ASC IP-MS to identify proteins that i...

ORGANISM(S): Mus musculus (Mouse)

2026-06-29 | PXD054933 | Pride

Asc Mouse bmdm Lps and atp Nlrp3 inflammasome

TMV-derived Small RNAs Reveals Role for Arabidopsis thaliana RNA-dependent RNA Polymerases in Viral siRNA Biogenesis

Using a crucifer-infecting strain of Tobacco Mosaic Virus (TMV-Cg) and Arabidopsis thaliana as a model system, we analyzed the viral small RNA profile in wild-type plants as well as rdr mutants by applying small RNA deep sequencing technology. Over 100,000 TMV-Cg-specific small RNA reads, mostly of...

ORGANISM(S): Youcai mosaic virus

2009-03-24 | E-GEOD-12918 | biostudies-arrayexpress

Cebpa regulates gene transcription in basophils

To investigate the mechanisms by which C/EBPa drives basophil differentiation and maintains basophil identity, we examined whether or not C/EBPa promotes basophil molecular programming and simultaneously represses mast cell molecular programming. We performed genome-wide gene expression profiling on...

ORGANISM(S): Mus musculus

2013-04-01 | E-GEOD-41596 | biostudies-arrayexpress

Triglyceride induces ‌endoplasmic reticulum lipid bilayer stress to activate PERK and enhance antifungal immunity

Triglyceride synthesis promotes the activation of C-type lectin receptors signaling pathway upon fungal infection‌. Triglyceride synthesis induces endoplasmic reticulum lipid bilayer stress and activates the PERK kinase after fungal stimulation. PERK mediates autophagic degradation of SHP-1 to ampli...

ORGANISM(S): Mus Musculus

2026-01-12 | PXD072975 |

Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection

Lysosomal cathepsins regulate an exquisite range of biological functions, and their deregulation is associated with inflammatory, metabolic and degenerative disease in humans. Here, we identified a key cell-intrinsic role for cathepsin B as a negative feedback regulator of lysosomal biogenesis and a...