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In this study, roots of Rehmannia glutinosa were used as experimental material, and three tuber roots of Rehmannia glutinosa in extension stage (I), expansion stage (E) and mature stage (M) were selected as samples, The iTRAQ quantitative proteomic technology combined with two-dimensional liquid chr...
ORGANISM(S): Rehmannia glutinosa 
2022-02-17 | PXD025914 | Pride
In this study, we achieved the quantitative glycoproteomics analysis of a large cohort of clinical specimens including 100 Hepatocellular carcinoma (HCC) and 100 healthy control human serums by using an integrated platform.
ORGANISM(S): Homo Sapiens (human) 
Acute coronary syndrome (ACS) is a kind of cardiovascular disease caused by acute myocardial ischemia. The aim of this study was to use urine metabolomics to explore the potential biomarkers for the diagnosis of ACS and the changes in metabolites during the development of the disease.
ORGANISM(S): Homo Sapiens 
2024-12-03 | PXD058501 |
Reactive sulfane sulfur species such as persulfides (RSSH) and H2S2 are important redox regulators and closely linked to H2S signaling. However, the study of these species is still challenging due to their instability, high reactivity, and the lack of suitable donors to produce these species. Herein...
ORGANISM(S): Oryctolagus Cuniculus (ncbitaxon:9986) 
2024-02-07 | MSV000094034 | MassIVE

Cesarean section scar diverticulum (CSD) has become a formidable obstacle preventing women receiving CS from reproducing. However, the pathogenesis of CSD remains unexplored. In this study, we characterized the cervical microbiota, metabolome and endometrial transcriptome of women with CSD. Based...

2022-07-25 | MTBLS4967 | MetaboLights
Neovascular AMD (nAMD) and proliferative diabetic retinopathy (PDR) are major blinding retinal diseases characterized by pathological angiogenesis. Using data-independent acquisition (DIA) proteomics, we analyzed aqueous humor from nAMD, PDR, and cataract control patients. Among 3186 identified prot...
ORGANISM(S): Homo Sapiens 
2025-09-09 | PXD068217 |
Background: Distinguishing indeterminate pulmonary nodules remains a significant challenge in the early diagnosis of lung cancer, while proteomic biomarkers derived from the lesioned pulmonary lobe may provide crucial insights into their malignant progression. Methods: Our study cohort included thre...
ORGANISM(S): Homo Sapiens 
2025-11-25 | PXD071235 |
Proteomics Profile of right ventricular remodeling at compensatory stage (both PAB and MCT models)
ORGANISM(S): Rattus Norvegicus 
2024-10-22 | PXD057041 |
We analyzed samples of tumor tissue, plasma, and urine from a cohort of 27 ccRCC patients with T1-2 stage and 27 matched healthy controls, using liquid chromatography–mass spectrometry (LC-MS) for proteomic analysis. We integrated the differential proteins found in the three types of samples to expl...
ORGANISM(S): Homo Sapiens 
2023-06-20 | PXD043118 |
Characterization of the selectivity of SMN splicing modifiers in SMA type I fibroblasts by RNASeq In total 12 samples were analyzed, divided into four distinct groups (treated with SMN-C3 @ 500 nM; controls for SMN-C3; treated with SMN-C1 @ 100 nM; controls for SMN-C1) containing 3 replicates each.
ORGANISM(S): Homo sapiens 
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