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UnknownProspective proof-of-concept observational RESEarch about traditional herbal preparation Treatment for Chronic Obstructive Pulmonary Disease (RESET-COPD-1).

Background

Despite advances in medical science, chronic obstructive pulmonary disease (COPD) continues to impact patients' lives significantly, due to symptom management limitations. Cheongsangboha-tang (CSBHT; Qing Shang Bu Xia Tang) and Hyunggaeyeongyo-tang (HGYGT; Jing Jie Lian Qiao Tang)...
S-EPMC11464318 | biostudies-literature
UnknownIntegrated biomarker profiling of the metabolome associated with type 2 diabetes mellitus among Tibetan in China.

Introduction

Metabolomic signatures of type 2 diabetes mellitus (T2DM) in Tibetan Chinese population, a group with high diabetes burden, remain largely unclear. Identifying the serum metabolite profile of Tibetan T2DM (T-T2DM) individuals may provide novel insights into early T2DM diagnosis ...
S-EPMC10314538 | biostudies-literature
UnknownKey regulatory genes and signaling pathways involved in islet culture: a bioinformatic analysis.
Type 1 diabetes (T1D) is characterized by non-ideal mass and low survival rate of islets. Therefore, it is necessary to find intrinsic factors that prolong the survival of islets. This study aimed to track out hub genes and pathways in the process of islet culture by bioinformatic analysis. We downl...
S-EPMC7868784 | biostudies-literature
TranscriptomicsTracing pluripotency of human early embryos and embryonic stem cells by single cell RNA-seq
Find the casual relationship between gene expression network and cellular phenotype at single cell resolution. We collected donated human pre-implatation embryos, and the embryonic stem cells derived from them, isolate individual cells, prepared single cell cDNAs, and sequenced them by HiSeq2000. Th...
ORGANISM(S): Homo sapiens 
2013-08-10 | E-GEOD-36552 | biostudies-arrayexpress
ProteomicsLC-MSMS of endogenous purified lipoprotein transporter LolDF in Acinetobacter
LolDF-mediated lipoprotein transport LC-MSMS in Acinetobacter, endogenous purified LolD and LolF
ORGANISM(S): Acinetobacter sp. ADP1 
2026-08-04 | PXD081527 | Pride
Lipoprotein Lc-msms Loldf Acinetobacter 
UnknownInduction chemotherapy with nedaplatin, docetaxel and 5-fluorouracil followed by concurrent nedaplatin and radiotherapy in locoregionally advanced nasopharyngeal carcinoma: A single arm, open label, phase II clinical trial
Not available
S-EPMC12813063 | biostudies-literature
TranscriptomicsThe DNA methylation landscape of human early embryos
Our data provided a genome-wide DNA methylation landscape of human early development embryos, including human MII oocytes, sperm, zygotes, 2-cell to 8-cell embryos, morula, blastocyst and postimplantation embryos at single base resolution. In total, 44 samples including biological and technical repl...
ORGANISM(S): Homo sapiens 
2014-07-22 | E-GEOD-49828 | biostudies-arrayexpress
GenomicsWhole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the human brain
5-Hydroxymethylcytosine (hmC) is particularly abundant in mammalian brains with yetto be revealed functions. Here, we present genome-wide and single-base-resolutionmaps of hmC and mC in the human brain. We demonstrated that hmCs increasemarkedly from the fetal to the adult stage, and in the adult br...
ORGANISM(S): Homo sapiens 
2014-02-22 | E-GEOD-55249 | biostudies-arrayexpress
UnknownNotch1 regulates tongue cancer cells proliferation, apoptosis and invasion.
OBJECTIVES:Notch1 regulates tumor biology in a complex, context-dependent manner. The roles of Notch1 in tongue cancer are still controversial. The aim of this study is to investigate the roles of Notch1 in tongue cancer. MATERIALS AND METHODS:The expression of Notch1 was tested between tongue cance...
S-EPMC5884382 | biostudies-literature
UnknownA Charge Transfer Mediated Sequential Triplet Energy Transfer Model Beyond the Dexter Limit in Organic Photocatalysis.
Classical distance-dependent Dexter energy transfer models fail to account for the complex, geometry-sensitive kinetics observed in flexible and dynamically disordered organic photocatalytic systems. To resolve these persistent inconsistencies, particularly in photosensitized [2 + 2] cycloaddition r...
S-EPMC12648329 | biostudies-literature
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