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ProteomicsS-nitrosylation of p53 in A375 cells
Nitric oxide (NO) is a pleiotropic signaling molecule that affects numerous biological functions. One unique posttranslational modification of proteins by NO is termed S-nitrosylation (SNO), but the role in modulating key proteins’ function in melanoma has not been fully characterized. In the presen...
ORGANISM(S): Homo sapiens (Human) 
2025-07-21 | PXD031807 | Pride
A375 Mass spectrometry S-nitrosylation P53 Melanoma cells 
ProteomicsMelatonin confers saline-alkali tolerance by relieving nitrosative damage and S-nitrosylation of plasma membrane H+-ATPase 2 in tomato
Soil salination and alkalization are global problems impairing plant survival by disrupting REDOX homeostasis. Whether melatonin regulates REDOX homeostasis at nitrosative level, and thus affects plant saline-alkali tolerance remains unknown. In saline-alkali stress, excess nitric oxide (NO) causes ...
ORGANISM(S): 'Solanum lycopersicum' phytoplasma 
2025-04-28 | PXD056815 | Pride
Melatonin  nitric oxide  plasma membrane h+-atpase 2  saline-alkali stress  s-nitrosylation  tomato 
ProteomicsNitrosoproteomic Analysis Deciphers the S-Nitrosylome in Carbon Metabolism of Tea Leaves
Cysteine S-nitrosylation is a reversible protein post-translational modification and critically regulates the activity, localization and stability of proteins. Tea (Camellia sinensis (L.)) is one of the most thoroughly studied evergreen crop due to its broad non-alcoholic beverage and huge economic ...
ORGANISM(S): Camellia sinensis 
2020-05-26 | PXD012443 | Pride
Cysteine s-nitrosylation Camellia sinensis (l.) o. kuntze Carbon metabolism 
ProteomicsFAT-switch-based quantitative S-nitrosoproteomics reveals a key role of GSNOR1 in regulating ER functions
Reversible protein S-nitrosylation regulates a wide range of biological functions and physiological activities in plants. However, it is challenging to quantitively determine the S-nitrosylation targets and dynamics in vivo. In this study, we developed a highly sensitive and efficient fluorous affin...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2023-06-07 | PXD037504 | Pride
S-nitrosylation  fluorous affinity tags  er stress  transcription  proteomics  redox homeostasis 
ProteomicsH2S-mediated S-sulfhydration coordinates autophagy and infection of the rice blast fungus
Hydrogen sulfide (H2S), a potent signaling molecule, regulates cellular activities in plants and mammals through S-sulfhydration, a post-translational modification. The role of H2S and its molecular targets in fungi, however, remain unclear. Our study demonstrates that H2S, synthesized by cystathion...
ORGANISM(S): Oryza sativa (Rice) 
2025-06-12 | PXD063170 | Pride
S-sulfhydration h2s atg18 magnaporthe oryzae 
UnknownA New Type of Electron Relay Station in Proteins: Three-Piece S:Π∴S↔S∴Π:S Resonance Structure.
Not available
S-EPMC4476553 | biostudies-literature
TranscriptomicsTranscription profiling of S. cerevisiae response to the antifungal compound sampangine
Sampangine, a plant-derived alkaloid found in the Annonaceae family, exhibits strong inhibitory activity against the opportunistic fungal pathogens Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus. In the present study, transcriptional profiling experiments coupled with the analy...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-11 | E-GEOD-10073 | biostudies-arrayexpress
MetabolomicsRelease of Ecologically Relevant Metabolites by the Cyanobacterium, Synechococcus elongatus CCMP 1631
Phytoplankton are known to release organic compounds that fuel secondary production by heterotrophic bacteria. Here we show that an abundant marine cyanobacterium, Synechococcus elongatus, contributes a variety of nitrogen-rich and sulfur-containing compounds to dissolved organic matter. A combinati...
2015-01-26 | MTBLS155 | MetaboLights
GenomicsDNA methylation analysis of prostate cancer cell lines and tissues using Next Generation Sequencing
Beginning with precursor lesions, aberrant DNA methylation marks the entire spectrum of prostate cancer progression. We mapped the global DNA methylation patterns in prostate tissues (n=17) and cells (n=2) from fifty nanograms of genomic DNA using Methylplex-Next Generation Sequencing (M-NGS). A...
ORGANISM(S): Homo sapiens 
2011-05-09 | E-GEOD-27618 | biostudies-arrayexpress
TranscriptomicsExpression analysis of Streptomyces avermitilis NRRL8165 delta-aveI mutant
Investigation of whole genome gene expression level changes in Streptomyces avermitilis delta-aveI mutant, compared to the wild-type strain. The mutants analyzed in this study are further described in Chen L, Lu Y., Chen J, Zhang W, Shu D, Qin Z, Yang S, Jiang W. (2008) Characterization of a negativ...
ORGANISM(S): Streptomyces avermitilis 
2010-05-16 | E-GEOD-16892 | biostudies-arrayexpress
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