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Unknownquantms: a cloud-based pipeline for quantitative proteomics enables the reanalysis of public proteomics data.
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S-EPMC11399091 | biostudies-literature
ProteomicsThe secretome of the white-rot basidiomycete Abortiporus biennis LGAM 436 can cause significant modifications to polystyrene structure
This study focused on investigating the biocatalytic potential of the white-rot basidiomycete Abortiporus biennis LGAM 436 to modify the structure of different types of PS, including amorphous film with atactic stereochemistry and commercial EPS foam. The selection of this specific strain was mainly...
ORGANISM(S): Abortiporus biennis 
2025-04-24 | PXD058977 | Pride
Polystyrene Lfq Plastic pollution Biodegradation Abortiporus Fungi White-rot Secretome Quantms Dda 
ProteomicsKM-12 Whole Cell Lysate Proteomics
The KM-12 cell line, representative of colorectal cancer indications, was used to explore the effect that multiple compounds would have in the profile of transcription factor occupancy. Cells were dosed with 3 concentrations of each of the 5 compounds provided for 3 different timepoints. Both a chro...
ORGANISM(S): Homo sapiens (Human) 
2026-04-06 | PXD065035 | Pride
Lc-msms Colorectal cancer Timstof 
ProteomicsExamination of polyester-polyurethane degradation by Streptomyces sp. PU10
This study aimed to investigate the variations in the protein composition of Streptomyces sp. PU10 when cultivated with either Impranil (polyestere-polyurethane) or glucose as the carbon source. We analyzed both the intracellular and extracellular protein fractions to gain insights into the intricat...
ORGANISM(S): Streptomyces sp. PU10 
2024-03-29 | PXD047534 | Pride
Impranil. lfq Q exactive hf Streptomyces Bacteria Dda Lc-ms/ms 
ProteomicsKinome profiling of wild type and Ripk1 KO NIT-1 cells with or without proinflammatory cytokine stimulation
Type 1 diabetes (T1D) is characterized by autoimmune destruction of pancreatic β-cells, insulin insufficiency, and hyperglycemia. Receptor interacting protein kinase 1 (RIPK1) is a multifunctional regulator of cell fate with kinase and scaffolding functions. We previously identified RIPKs as regulat...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-10 | PXD068596 | Pride
Beta cells Kinase Inhibitor Bead Type 1 diabetes 
ProteomicsExtensive peripheral immunoglobulin repertoire analyses in people with multiple sclerosis reveal disease-specific signatures and distinct treatment effects of disease modifying drugs
B cells are crucial players in the pathogenesis of multiple sclerosis (MS), however, limited information is available on peripheral immunoglobulin (Ig) repertoires of people with MS (pwMS) in comparison to healthy individuals and during different treatments. Next generation sequencing of Ig heavy ch...
ORGANISM(S): Homo sapiens (Human) 
2026-04-27 | PXD075641 | Pride
Immunoglobulin proteome Keywords: multiple sclerosis (ms) Disease modifying drugs (dmds) Epstein-barr virus (ebv) Immunoglobulin repertoire B cells 
ProteomicsGenomic, Proteomic, and Biochemical Study of Pleurotus pulmonarius Secretome and Its Role in Biomass Saccharification
Pleurotus species include edible mushrooms that can grow on a broad range of lignocellulosic substrates by secreting a coordinated system of hydrolytic and oxidative enzymes. This flexibility offers opportunities to valorize agro-industrial residues for production of food and biomaterials using sust...
ORGANISM(S): Pleurotus pulmonarius 
2025-11-03 | PXD065010 | Pride
ProteomicsMulti-omics insights into the response of Aspergillus parasiticus to long-chain alkanes in relation to polyethylene modification
In this study, we employed a multi-omics approach to study the ability of Aspergillus parasiticus MM36, an isolate derived from Tenebrio molitor intestines, to metabolize long-chain alkanes (lcAlk) and secrete enzymes able to modify polyethylene (PE). Following genome sequencing, assembly, and annot...
ORGANISM(S): Aspergillus parasiticus 
2025-05-13 | PXD058271 | Pride
Multi-omics Alkanes Aspergillus Plastic pollution Biodegradation Extracellular Fungi Secretome 
ProteomicsActivity-Targeted SIP-Metaproteomics of a Full-Scale Biogas Facility
In this work, two BONCAT enrichment techniques were evaluated against a conventional untargeted metaproteomics approach for their ability to enrich the SIP signal of SAOB in metaproteomics data from an anaerobic microbiome. The first BONCAT enrichment was based on sorting active cells using fluoresc...
ORGANISM(S): Anaerobic Digester Metagenome (ncbitaxon:1263854) 
2024-10-24 | MSV000096205 | MassIVE
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