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ProteomicsR2-P2 rapid-robotic phosphoproteomics enables multidimensional cell signaling studies
Recent developments in mass spectrometry-based proteomics have enabled systems-level studies of cellular signaling, where >10,000 phosphosites can be routinely identified and quantified. Yet, current analyses are limited in throughput, reproducibility, and robustness, hampering experiments that invo...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2019-12-12 | PXD013453 | Pride
Phosphoproteomics / signaling / mapk / mass spectrometry / sp3 / dia/ r2-p2 
UnknownR2-P2 rapid-robotic phosphoproteomics enables multidimensional cell signaling studies.
Not available
S-EPMC6920700 | biostudies-literature
ProteomicsAutomated Enrichment of Phosphotyrosine Peptides for High-Throughput Proteomics
Phosphotyrosine (pY) enrichment is critical for expanding fundamental and clinical understanding of cellular signaling by mass spectrometry-based proteomics. However, current pY enrichment methods exhibit a high cost per sample and limited reproducibility due to expensive affinity reagents and manua...
ORGANISM(S): Homo sapiens (Human) 
2023-05-05 | PXD041271 | Pride
Hela Lc-msms Kingfisher Orbitrap eclipse Orbitrap exploris 480 Phosphotyrosine enrichment 
ProteomicsThe regulatory landscape of the yeast phosphoproteome – quantitative proteomics DIA data
We systematically exposed the yeast Saccharomyces cerevisiae to a wide array of 101 perturbations and generated a quantitative mass spectrometry-based atlas of early phosphoproteomic responses. Perturbations covered broad classes of environmental, chemical, and drug perturbations and systematically ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-08-27 | PXD034997 | Pride
Signaling Dia Orbitrap exploris 480 Stress response Saccharomyces cerevisiae Budding yeast R2-p2 
ProteomicsThe regulatory landscape of the yeast phosphoproteome – quantitative phosphoproteomic DIA data
We systematically exposed the yeast Saccharomyces cerevisiae to a wide array of 101 perturbations and generated a quantitative mass spectrometry-based atlas of early phosphoproteomic responses. Perturbations covered broad classes of environmental, chemical, and drug perturbations and systematically ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-08-27 | PXD035050 | Pride
Signaling Dia Phosphoproteomics Orbitrap exploris 480 Ptm Saccharomyces cerevisiae Phosphatase Budding yeast R2-p2 Stress response Kinase Phosphorylation 
ProteomicsThe regulatory landscape of the yeast phosphoproteome – ultra-deep reference phosphoproteomic DDA data
We systematically exposed the yeast Saccharomyces cerevisiae to a wide array of 101 perturbations and generated a quantitative mass spectrometry-based atlas of early phosphoproteomic responses. Perturbations covered broad classes of environmental, chemical, and drug perturbations and systematically ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-08-27 | PXD035029 | Pride
Signaling Phosphoproteomics Orbitrap exploris 480 Orbitrap eclipse Ptm Saccharomyces cerevisiae Stress response Dda Phosphorylation Phosphatase Budding yeast Fractionation R2-p2 Kinase 
TranscriptomicsiPS2-multi-seq on early pasage (P3) iPS2-seq targeted hiPSC
We aimed to identify the nature of iPSC and iPSC-neuro clones identified in E-MTAB-14065. We evaluated the combined effect on the epigenome and transcription at the single-cell level. This experiment demonstrated the importance of clonal tracking when performing scRNAseq screenings and allowed us to...
ORGANISM(S): Homo sapiens 
2025-10-27 | E-MTAB-15332 | biostudies-arrayexpress
Genomicspermafrost metagenome
Permafrost peat microbial communities from Stordalen, Sweden - P2-R2-A metagenome
PRJNA1315871 | ENA
Genomicspermafrost metagenome
Permafrost peat microbial communities from Stordalen, Sweden - P2-R2-B metagenome
PRJNA1315872 | ENA
Genomicspermafrost metagenome
Metatranscriptome of permafrost peat microbial communities from Stordalen, Sweden - P2-R2-B
PRJNA1341545 | ENA
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