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MetabolomicsMetabolic and lipidomic characterization of radioresistant MDA-MB-231 human breast cancer cells to investigate potential therapeutic targets
Not available
ORGANISM(S): Homo sapiens 
ST001920 | MetabolomicsWorkbench
ProteomicsTargeted proteomic analysis of small GTPases in radioresistant breast cancer cells
Radiotherapy benefits more than 50% of cancer patients and cures 40% of them, where ionizing radiation deposits energy to cells and tissues, thereby eliciting DNA damage and resulting in cell death. Small GTPases are a superfamily of proteins that play critical roles in cell signaling. Several small...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD034360 | Pride
Breast cancer Radioresistance Radiation therapy Mrm Targeted proteomics Small gtpase 
GenomicsEstablishment of radioresistant MCF-7 breast cancer cell line
Establishment of radioresistant MCF-7 breast cancer cell line
PRJNA865694 | ENA
ProteomicsTargeted Profiling of Epitranscriptomic Reader, Writer and Eraser Proteins in Radioresistant Breast Cancer Cells
Epitransciptomic reader, writer and eraser (RWE) proteins recognize, install, and remove modified nucleosides in RNA, which are known to play essential roles in RNA processing, splicing, and stability. Here, we established a liquid chromatography–parallel reaction monitoring (LC-PRM) method for high...
ORGANISM(S): Homo sapiens (Human) 
2022-08-15 | PXD030387 | Pride
Epitransciptomic reader Lc-prm Radioresistant breast cancer Trmt1 Writer and eraser (rwe) proteins 
GenomicsDevelopment and Characterisation of Acquired Radioresistant Breast Cancer Cell Lines.
Development and Characterisation of Acquired Radioresistant Breast Cancer Cell Lines.
PRJNA494562 | ENA
TranscriptomicsTranscriptomic profiling of AR knockdown in human triple-negative breast cancer Hs578T cells
This study aimed to investigate transcriptomic alterations induced by androgen receptor (AR) silencing in the radioresistant Hs578T triple-negative breast cancer (TNBC) cells. Using siRNA-mediated knockdown of AR, RNA sequencing was performed to identify genes and pathways associated with AR signali...
ORGANISM(S): Homo sapiens 
2025-11-14 | E-MTAB-16017 | biostudies-arrayexpress
TranscriptomicsEstablishment of radioresistant MCF-7 breast cancer cell line
To explore elements contributing to radioresistance in breast cancer, we established radioresistant human breast cancer cell line MCF-7.
ORGANISM(S): Homo sapiens 
2022-08-06 | GSE210411 | GEO
ProteomicsDiscovery of biomarkers in radioresistant MCF7R breast cancer xenografts
Radioresistance of tumors is not completely understood. Our previous studies have shown that MCF-7 breast cancer cell line exposed to 6 Gy and allowed to recover for 7 days (D7-6G) developed radio-resistance. In this study, we have tested the ability of these cells to form tumors in SCID mice and ch...
ORGANISM(S): Homo sapiens (Human) 
2021-01-04 | PXD022506 | Pride
Mcf7 Radioresistance Xenografts Breast cancer 
UnknownTargeting radioresistant breast cancer cells by single agent CHK1 inhibitor via enhancing replication stress.
Not available
S-EPMC5085184 | biostudies-literature
UnknownCPT1A/2-Mediated FAO Enhancement-A Metabolic Target in Radioresistant Breast Cancer.
Not available
S-EPMC6873486 | biostudies-literature
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