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UnknownA multiplexed microflow LC-MS/MS-PRM assay for serologic quantification of IgG N- and HPX O- glycoforms in liver fibrosis.
Not available
S-EPMC9837073 | biostudies-literature
UnknownQuantitative Analysis of α-1-Antitrypsin Glycosylation Isoforms in HCC Patients Using LC-HCD-PRM-MS.
Not available
S-EPMC7373126 | biostudies-literature
ProteomicsTargeted Quantitative Profiling of Epitranscriptomic Reader, Writer and Eraser Proteins Revealed Potential Crosstalk between N6-Methyladenosine and Other RNA Modifications
N⁶-methyladenosine (m6A) and its reader, writer, and eraser (RWE) proteins assume crucial roles in regulating the splicing, stability, and translation of mRNA. To our knowledge, no systematic investigations have been conducted about the crosstalk between m6A and other modified nucleosides in RNA. He...
ORGANISM(S): Homo sapiens (Human) 
2022-09-24 | PXD036032 | Pride
Lc-prm N6-methyladenosine Epitranscriptomic reader Writer and eraser proteins 
ProteomicsTargeted Profiling of Epitranscriptomic Reader, Writer and Eraser Proteins in Radioresistant Breast Cancer Cells
Epitransciptomic reader, writer and eraser (RWE) proteins recognize, install, and remove modified nucleosides in RNA, which are known to play essential roles in RNA processing, splicing, and stability. Here, we established a liquid chromatography–parallel reaction monitoring (LC-PRM) method for high...
ORGANISM(S): Homo sapiens (Human) 
2022-08-15 | PXD030387 | Pride
Epitransciptomic reader Lc-prm Radioresistant breast cancer Trmt1 Writer and eraser (rwe) proteins 
ProteomicsLC-MS/MS-PRM Quantification of IgG glycoforms using stable isotope labeled IgG1 Fc glycopeptide standard
LC-MS/MS-PRM Quantification of IgG glycoforms using stable isotope labeled IgG1 Fc glycopeptide standard
ORGANISM(S): Homo Sapiens (human) 
2024-01-16 | PXD039462 | JPOST Repository
ProteomicsPRM-MS quantitative analysis of isomeric N-glycopeptides derived from human serum haptoglobin of patients with cirrhosis and hepatocellular carcinoma
Comprehensive LC-PRM-MS approach where a targeted parallel reaction monitoring (PRM) strategy was coupled to a powerful LC system to study the microheterogeneity of serum haptoglobin (Hp) extracted from 15 patients with cirrhosis and 15 with hepatocellular carcinoma (HCC).
ORGANISM(S): Homo sapiens (Human) 
2021-09-10 | PXD023719 | Pride
N-glycopeptides Prm Hepatocellular carcinoma (hcc) Haptoglobin Cirrhosis 
ProteomicsTargeted LC-MS/MS analysis of oSCRIB protein in HeLa cells.
LC-MS/MS analysis of small HeLa proteins (approximately 10–15 kDa) for detecting oSCRIB protein with Parallel Reaction Monitoring (PRM) mode.
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD027841 | Pride
Human Prm Hela Lc-ms/ms 
ProteomicsA multiplexed microflow LC-MS/MS-PRM assay for serologic quantification of IgG N- and HPX O- glycoforms in liver fibrosis
In this study, we introduce a targeted microflow LC-MS/MS-PRM method for the quantification of multiple glycopeptides in unfractionated serum samples. The entire preparation of 16 samples in a batch is completed within 3 h, and the LC-MS quantification of all the glycoforms in a sample is completed ...
ORGANISM(S): Homo Sapiens (human) 
2023-10-25 | PXD037687 | JPOST Repository
ProteomicsProteomic profiling and PRM analysis for quantification of heterologous antigens in HIV-1 Gag VLPs
In this study, we evaluated HIV-1 Gag Virus Like Particles (VLPs) for the display of heterologous membrane proteins in their native conformation and lipid environment. The overexpressed membrane protein was quantified in the VLPs by LC-MS/MS based PRM analysis.
ORGANISM(S): Homo sapiens (Human) 
2026-02-20 | PXD074653 | Pride
Vlps Prm Lc-ms/ms 
MetabolomicsLiquid Chromatography-Mass Spectrometry Quantification of Phytochemicals in Withania somnifera Using Data-Dependent Acquisition, Multiple-Reaction-Monitoring, and Parallel-Reaction-Monitoring with an Inclusion List

Characterization of botanical extracts by mass spectrometry-based metabolomics analysis helps in determining the phytochemical composition that underlies their bioactivity and potential health benefits, while also supporting reproducibility of effects in clinical trials. The quantification of sev...

2024-07-10 | MTBLS10418 | MetaboLights
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