Purpose: Prostate-specific membrane antigen-targeted radioligand therapy (PSMA-RLT) is effective against prostate cancer (PCa), but all patients relapse eventually. Poor understanding of the underlying resistance mechanisms represents a key barrier to development of more effective RLT. We investigat...
Amyotrophic lateral sclerosis (ALS) consists in the progressive degeneration of motor neurons, caused by mechanisms that are poorly understood and for which there is no cure. Some of the cellular perturbations associated with ALS can be detected in peripheral cells, including lym-phocytes from blood...
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Compartmentation of cAMP signaling in cardiac myocytes: a computational study.
Iancu RV, Jones SW, Harvey RD. Biophys J
2007 May 1;92(9):3317-31 17293406
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Abstract:
Recepto...
Quantitative proteomic and phosphoproteomic analysis of the human T-ALL cell line, CCRF CEM, following 12 hours of ATR inhibiton using the Vertex drug, VE-822.
