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TranscriptomicsWnt ligands from the embryonic surface ectoderm regulate bimetallic strip optic cup morphogenesis in the mouse
Wnt signaling in early eye development, specifically the lens placode shows expression of 12 out of 19 Wnt ligands. We these Wnt activities were suppressed using conditional deletion of Wntless, dramatic phenotypic changes in morphogensis occurred. Microarray analysis of the genes that were changed...
ORGANISM(S): Mus musculus 
2015-01-22 | E-GEOD-65154 | biostudies-arrayexpress
ProteomicsPhosphoproteomics reveals key regulatory kinases and modulated pathways involved in tumorigenesis of ovarian cancer
The present study comprehensively revealed the molecular characteristics in relation to OC and identified significantly distinct phosphorylated sites and phosphorylated proteins underlying the syndrome. The results here dissected regulatory elements (especially kinases) and pathways involved in canc...
ORGANISM(S): Homo Sapiens 
2019-12-31 | PXD016183 |
UnknownExome sequencing identifies a novel gene, WNK1, for susceptibility to pelvic organ prolapse (POP).
Not available
S-EPMC4349638 | biostudies-literature
UnknownMetal-ligand Lability and Ligand Mobility Enables Framework Transformation via Ligand Release in a Family of Crystalline 2D Coordination Polymers.
Not available
S-EPMC9543667 | biostudies-literature
UnknownEffect of miR-142-3p on the M2 macrophage and therapeutic efficacy against murine glioblastoma.
Not available
S-EPMC4271080 | biostudies-literature
TranscriptomicsmiRNA expression profiles of peripheral monocytes and glioblastoma-infiltrating macrophages
MicroRNAs (miRNAs) are non-coding molecules involved in post-transcriptional gene regulation that have been shown to modulate tumor cell proliferation and apoptosis and to act as oncogenes or tumor-suppressor genes. Although miRNAs have been linked to tumor progression, the connection between tumor-...
ORGANISM(S): Homo sapiens 
2014-09-23 | E-GEOD-51332 | biostudies-arrayexpress
UnknownmiRNA expression profiles of peripheral monocytes and glioblastoma-infiltrating macrophages
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-51332 | biostudies-other
ProteomicsThe sequence of Fully Synthetic peptides, Phosphorylated Tau181, Tau217, and Tau231 Calibrators, have been confirmed by MALDI-ISD analysis
We designed novel calibrators that include three phosphorylated Tau sites: Tau (1-22)-pT231, Tau (1-22)-pT217, and Tau (1-22)-pT181, respectively. Our synthesized peptides have various advantages compared with GSK3β-phosphorylated Tau-441. The novel fully synthesized calibrators not only improved th...
ORGANISM(S): Homo Sapiens 
2023-11-24 | PXD047248 |
UnknownREST-DRD2 mechanism impacts glioblastoma stem cell-mediated tumorigenesis.
Not available
S-EPMC6556851 | biostudies-literature
UnknownImmunological dynamics in orthotopic compared with subcutaneous murine models of HPV-positive oropharyngeal cancer.
Not available
S-EPMC12746710 | biostudies-literature
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