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ProteomicsMelanoma BRAFV600E induced proteome
By analyzing of the changes in proteome mediated by the oncogene BRAFV600E in melanoma cells we provide new insights on the pathways upregulated in these cells and possible new targets for therapy.
ORGANISM(S): Mus musculus (Mouse) 
2018-06-25 | PXD008010 | Pride
Brafv600e Mouse Melanoma 
ProteomicsWobble tRNA modification dependent proteome
We want to assess the features of proteins whose translation depends on the mcm5s2 modification of urifdine in position 34 of some tRNAs.
ORGANISM(S): Homo sapiens (Human) 
2021-02-24 | PXD019620 | Pride
Trna modification Elongator Cancer 
TranscriptomicsReprogramming of a B cell line into macrophages
Transcription factor induced reprogramming of one specialized cell type into another is a promising approach for regenerative medicine. However, the process still remains poorly understood, in large part because of the lack of adequate experimental models. Here we describe a robust cell reprogrammin...
ORGANISM(S): Mus musculus 
2009-11-22 | E-GEOD-17316 | biostudies-arrayexpress
TranscriptomicsC/EBPα induces highly efficient macrophage transdifferentiation of selected B-lymphoma /leukemia cell lines and impairs their tumorigenicity
Earlier work demonstrated that the transcription factor C/EBPα can convert immature and mature murine B lineage cells into functional macrophages. Testing >20 human lymphoma and leukemia B-cell lines, we found that most can be transdifferentiated at least partially into macrophage-like cells, provi...
ORGANISM(S): Homo sapiens 
2013-03-14 | E-GEOD-44700 | biostudies-arrayexpress
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