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ProteomicsProteomic analysis of Tks5 interactome to identify common marker of all types of invadosomes.
Invasion of the extracellular matrix is needed for physiological events such as wound healing but is also required at different stages of the metastatic process. The ability to progress and invade through the extracellular matrix is a characteristic shared by both normal and cancer cells through the...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-26 | PXD046512 | Pride
Invadosomes Nih cells Tks5 Quantitative proteome Translation 
ProteomicsProteomic analysis of Tks5 interactome to identify common marker of all types of invadosomes.
Invasion of the extracellular matrix is needed for physiological events such as wound healing but is also required at different stages of the metastatic process. The ability to progress and invade through the extracellular matrix is a characteristic shared by both normal and cancer cells through the...
ORGANISM(S): Homo sapiens (Human) 
2025-11-26 | PXD046515 | Pride
Invadosomes Tks5 Quantitative proteome Translation A431 cells 
TranscriptomicsGermfree C57BL/6J mice are resistant to high fat diet-induced insulin resistance and have altered cholesterol metabolism
Germfree (GF) mice have been used as a model to study the contribution of the intestinal microbiota to metabolic energy balance of the host. Despite a wealth of knowledge accumulated since the 1940’s, the response of GF mice to a high fat diet is largely unknown. In the present study, we compared th...
ORGANISM(S): Mus musculus 
2010-08-20 | E-GEOD-19038 | biostudies-arrayexpress
TranscriptomicsMouse myoblasts grown on Fibronectin or Collagen I for 72 hours
The goal of this study was to investigate the transcriptional regulation in cells grown on Fibronectin when compared to Collagen I 3 samples per condition
ORGANISM(S): Mus musculus 
2016-07-04 | E-GEOD-81225 | biostudies-arrayexpress
TranscriptomicsBenefits of a 6 week supplementation of sebacic acid on a mouse model of type 2 diabetes (db/db mice)
This study aimed at investigating the impact of chronic ingestion of sebacic acid (SA), a 10 carbons medium-chain dicarboxylic acid, on glycemic control in a mouse model of type 2 diabetes (db/db mice). Three groups of 15 mice were fed for 6 weeks either a chow diet (Ctrl), or a chow diet supplement...
ORGANISM(S): Mus musculus 
2010-10-29 | E-GEOD-21083 | biostudies-arrayexpress
TranscriptomicsConsequences of exchanging carbohydrates for proteins in the cholesterol metabolism of mice fed a high-fat diet
Dietary proteins have profound effects on lipid metabolism but the mechanism remains to be elucidated. In the present study, we examined the temporal impact of dietary proteins in isoenergetic high fat diets on lipid metabolism of C57BL/6J mice. Mice were first fed a low protein (P) to carbohydrate ...
ORGANISM(S): Mus musculus 
2012-12-19 | E-GEOD-20260 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of muscle gene expression in response to an intense cycling exercise. Effect of two protein-leucine enriched diets
Protein-leucine supplement ingestion following strenuous endurance exercise accentuates skeletal-muscle protein synthesis and adaptive molecular responses, but the underlying transcriptome is uncharacterized. In a randomized single-blind triple-crossover design, 12 trained men completed 100 min of h...
ORGANISM(S): Homo sapiens 
2015-11-23 | E-GEOD-44818 | biostudies-arrayexpress
TranscriptomicsTranscriptome and translational signaling following endurance exercise in trained skeletal muscle: impact of dietary protein
Impact of protein ingestion following 1 h intense cycling on the induced transcriptome and signaling in biopsy samples from endurance-trained men, relative to isocaloric control Single blind, randomized, crossover design comprising two experimental blocks. During the blocks, exercise and diet were c...
ORGANISM(S): Homo sapiens 
2011-11-21 | E-GEOD-27285 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of strains of Leishmania infantum, Leishmania major and Leishmania tarentolae
The genomic DNAs of strains JPCM5 and 263 of L. infantum, strains LV39 and Friedlin of L. major and strains Parrot-TarII and S125 of L. tarentolae were used in comparative genomic hybridizations to reveal the intra-species and inter-species gene content, and to validate L. tarentolae Parrot-TarII ge...
ORGANISM(S): Leishmania tarentolae 
2011-10-20 | E-GEOD-27184 | biostudies-arrayexpress
ProteomicsTumor microenvironment remodeling by cancer cell-released tracks on type I collagen
Metastasis is the leading cause of cancer-related deaths. During this process, tumor cells acquire invasive and migratory capacities in order to invade the surrounding tissues. To achieve this, the tumor microenvironment is altered to facilitate cancer cells proliferation and dissemination. Multiple...
ORGANISM(S): Homo sapiens (Human) 
2026-02-24 | PXD035152 | Pride
Extracellular vesicles Type i collagen fibers Migration 
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