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ProteomicsChronic pancreatitis vs pancreatic cancer LC-MS
Age-standardized incidence rates for pancreatic cancer (PC) in men have increased by 25% from 1957 to 2011 in Finland. The average age of diagnosis for PC is 69 years in Nordic males, whereas the average age of diagnosis of chronic pancreatitis (CP) is 40-50 years, but the cases overlap in age. By r...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-08-31 | MSV000082883 | MassIVE
ProteomicsPLASMA PROTEOMIC ANALYSIS OF RARE BMI-DISCORDANT MONOZYGOTIC TWIN PAIRS
The aim of the current study is to establish the effect of excess body wiehgt and liver fat on plasma proteomic profile without interference from genetic variation. Label-free proteomics (HDMSE) was performed on plasma samples of young healthy monozygotic twins who were discordant for BMI. the twins...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000084372 | MassIVE
ProteomicsQuantitative proteomics of bloodstream infection
We have performed LC-MS based plasma proteomics of twenty febrile patients coming in at Peijas Hospital, Helsinki University Hospital (Vantaa, Finland). At the same time, blood culture was performed to classify the patients to blood culture positive and negative for bloodstream infections. Blood cul...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-10 | MSV000081709 | MassIVE
ProteomicsQuantitative glycoproteomics of human milk and their association with atopic disease
Children who grow up on farms have a lower risk of developing childhood atopic disease. Although human milk proteins are heavily glycosylated, there is a lack of studies investigating the milk glycoproteome. In this study, we have used label-free quantitative proteomics to analyze milk samples from ...
ORGANISM(S): Homo sapiens (Human) 
2022-06-09 | PXD026644 | Pride
Human Mass spectrometry Milk N-glycoproteins 
ProteomicsHuman Uirnary Extracellular vesicles Proteomics LC-MS
A proteomic analysis utilizing UDMSE was performed on exosomes and microvesicle fractions isolated from human urine. more than 2 unique peptides containing proteins were quantified (586). exosomes and microvesicles were compared to each other in a quantitative manner.
ORGANISM(S): Homo sapiens (Human) 
2022-03-02 | PXD005729 | Pride
Microvesicles Lc-ms Urinary exosomes 
ProteomicsLabel-free proteomics reveal that plasma protein expression differs between colorectal cancer patients according to tumor stage, location, patient survival, preoperative radiotherapy status, or gender.
Colorectal cancer (CRC) is the third most common cancer worldwide and is a heterogeneous disease, with differences between cancer in the right colon, left colon, and rectum. In this study, plasma samples from CRC patients with varying stage (II or III), primary tumor location (right colon, left colo...
ORGANISM(S): Homo sapiens (Human) 
2019-08-22 | PXD013150 | Pride
Proteomics Human colorectal cancer Udmse Label-free quantitation 
ProteomicsChronic pancreatitis vs pancreatic cancer LC-MS
Age-standardized incidence rates for pancreatic cancer (PC) in men have increased by 25% from 1957 to 2011 in Finland. The average age of diagnosis for PC is 69 years in Nordic males, whereas the average age of diagnosis of chronic pancreatitis (CP) is 40-50 years, but the cases overlap in age. By r...
ORGANISM(S): Homo sapiens (Human) 
2017-06-09 | PXD005144 | Pride
Multivariate data analysis Lc-ms Chronic pancreatitis Pancreatic ductal adenocarcinoma Label-free qunatification Pancreatic cancer 
ProteomicsDifferential proteomics of human seminal fluid Normo Vs Astehnozoospermia
Scarcely understood defects lead to asthenozoospermia which results in poor fertility outcomes. Incomplete knowledge of these defects hinders the development of new therapies and reliance on interventional therapies, such as in vitro fertilization, increases. Sperm cells, being transcriptionally and...
ORGANISM(S): Homo sapiens (Human) 
2016-12-13 | PXD004098 | Pride
Human Spermatozoa Asthenozoospermia Seminal plasma 
ProteomicsBloodstream infection N-glycoproteomics
Here we have performed targeted quantitative N-glycoproteomics from plasma samples of patients with confirmed positive blood culture together with age and sex matched febrile controls with negative blood culture reports. Three hundred and sixty eight potential N-glycopeptides were quantified by mass...
ORGANISM(S): Homo sapiens (Human) 
2018-04-09 | PXD009048 | Pride
Sepsis Human plasma Bloodstream infection N-glycoproteomics 
ProteomicsQuantitative proteomics of bloodstream infection
We have performed LC-MS based plasma proteomics of twenty febrile patients coming in at Peijas Hospital, Helsinki University Hospital (Vantaa, Finland). At the same time, blood culture was performed to classify the patients to blood culture positive and negative for bloodstream infections. Blood cul...
ORGANISM(S): Homo sapiens (Human) 
2017-02-28 | PXD005022 | Pride
Mse Sepsis Bloodstream infection 
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