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MetabolomicsMetabolome and proteome changes in skeletal muscle and blood of pre-weaning calves fed leucine and threonine supplemented diets

In pre-weaning calves, both leucine and threonine play important roles in growth and muscle metabolism. In this study, metabolomics, proteomics and clinical chemistry were used to assess the effects of leucine and threonine supplementation added to milk replacer on 14 newborn Holstein male calves...

2020-02-20 | MTBLS1045 | MetaboLights
MetabolomicsTen Mouse Organs Proteome and Metabolome Atlas from Adult to Aging

The complexity of the aging process, encompassing numerous organs and systems, poses a significant challenge in identifying and targeting key factors that drive age-related decline. The multi-organ synchronous molecular intricacies underlying natural aging remain elusive. Here we presented a data...

2025-08-29 | MTBLS10642 | MetaboLights
ProteomicsRetinal proteome profiling of inherited retinal degeneration across three different mouse models suggests common drug targets in retinitis pigmentosa
Inherited retinal degenerations (IRDs) are a leading cause of blindness among the young population in the developed world. Approximately half of IRDs initially manifest as gradual loss of night vision and visual fields, characteristic of retinitis pigmentosa (RP). Due to challenges in genetic testi...
ORGANISM(S): Mus musculus (Mouse) 
2024-10-10 | PXD052547 | Pride
Retinal degeneration Retinal proteome : inherited retinal degenerations Rd10 Retinitis pigmentosa 
ProteomicsRetinal proteome profiling of inherited retinal degeneration across three different mouse models suggests common drug targets in retinitis pigmentosa
Inherited retinal degenerations (IRDs) are a leading cause of blindness among the young population in the developed world. Approximately half of IRDs initially manifest as gradual loss of night vision and visual fields, characteristic of retinitis pigmentosa (RP). Due to challenges in genetic testi...
ORGANISM(S): Mus musculus (Mouse) 
2024-10-10 | PXD052549 | Pride
Retinal degeneration Retinal proteome Rpe65-/- Inherited retinal degenerations Rd10 Retinitis pigmentosa P23h 
ProteomicsRetinal proteome profiling of inherited retinal degeneration across three different mouse models suggests common drug targets in retinitis pigmentosa
Inherited retinal degenerations (IRDs) are a leading cause of blindness among the young population in the developed world. Approximately half of IRDs initially manifest as gradual loss of night vision and visual fields, characteristic of retinitis pigmentosa (RP). Due to challenges in genetic testi...
ORGANISM(S): Mus musculus (Mouse) 
2024-10-10 | PXD052554 | Pride
Retinal degeneration Retinal proteome Rpe65-/- Inherited retinal degenerations Rd10 Retinitis pigmentosa P23h 
ProteomicsThe proteome of normal human iris, ciliary body, retinal pigment epithelium, and choroid
The iris is a fine structure that controls the amount of light that enters the eye. The ciliary body controls the shape of the lens and produces aqueous humor. The retinal pigment epithelium and choroid (RPE/choroid) are essential in supporting the retina and absorbing light energy that enters the e...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-29 | MSV000081766 | MassIVE
ProteomicsRetinal proteome profiling of inherited retinal degeneration across three different mouse models suggests common drug targets in retinitis pigmentosa
Inherited retinal degenerations (IRDs) are a leading cause of blindness among the young population in the developed world. Approximately half of IRDs initially manifest as gradual loss of night vision and visual fields, characteristic of retinitis pigmentosa (RP). Due to challenges in genetic testi...
ORGANISM(S): Mus musculus (Mouse) 
2024-10-10 | PXD052555 | Pride
Retinal degeneration Retinal proteome Rpe65-/- Inherited retinal degenerations Rd10 Retinitis pigmentosa P23h 
ProteomicsHBS1L-deficient retinal proteomics analysis revealing critical role of ribosomal rescue factor in the photoreceptor cell development
Inherited retinal diseases (IRDs) encompass a genetically diverse group of conditions in which mutations in genes critical to retinal function lead to progressive loss of photoreceptor cells and subsequent visual impairment. A handful of ribosome-associated genes have been implicated in retinal diso...
ORGANISM(S): Mus musculus (Mouse) 
2024-07-25 | PXD045660 | Pride
Hbs1l Retinal degeneration Ribosomal rescue 
Proteomicscryo-EM study of bovine retinal pigment epithelium cell lysate
This is the proteomic analysis data of bovine retinal pigment epithelium cell lysate subjected to cryo-EM study.
ORGANISM(S): Bos taurus (Bovine) 
2023-01-02 | PXD037186 | Pride
Cryo-em Bovine Retinal pigment epithelium cell 
ProteomicsRetinal proteome analysis reveals region-specific change in the rabbit myopia model
Uncovering region-specific change in myopic retina can provide the clue for explaining the pathogenesis of myopia progression. After imposing form deprivation myopia (FDM) on the right eye of 6-week-old rabbits, we investigated the proteome profile of each retinal region (central, mid periphery, an...
ORGANISM(S): Oryctolagus cuniculus (Rabbit) 
2023-03-10 | PXD038552 | Pride
Retina Rabbit Myopia Lc-ms/ms 
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