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TranscriptomicsBase J represses genes at the end of polycistronic gene clusters in Leishmania major by promoting RNAP II termination
Base J and H3.V promote RNA Polymerase (RNAP) II termination within polycistronic gene clusters in the kinetoplastid species Trypanosoma brucei. Although base J has been shown to promote RNAP II termination in the related kinetoplastid species Leishmania major and Leishmania tarentolae, the role of ...
ORGANISM(S): Leishmania major 
2016-07-20 | E-GEOD-77632 | biostudies-arrayexpress
ProteomicsExposure to the Florida red tide dinoflagellate, Karenia brevis, and its associated brevetoxins induces ecophysiological and proteomic alterations in Porites astreoides
As reef-building corals are increasingly being exposed to persistent threats that operate on both regional and global scales there is a pressing need to better understand the complex processes that diminish coral populations. This study investigated the impacts of the Florida Red Tide dinoflagellate...
ORGANISM(S): Karenia Brevis (ncbitaxon:156230) Porites Astreoides (ncbitaxon:104758) 
2019-10-08 | MSV000084432 | MassIVE
TranscriptomicsInvestigation of placental gene expression in obese women exposed to Metformin during pregnancy
Maternal obesity in pregnancy is associated with increased birth-weight, obesity and premature mortality in adult offspring. The Effect of Metformin on Maternal and Fetal Outcomes in Pregnant Obese Women (EMPOWaR) trial was a randomised, double-blind, placebo-controlled trial carried out to determin...
ORGANISM(S): Homo sapiens 
2019-01-31 | E-MTAB-6418 | biostudies-arrayexpress
TranscriptomicsInvestigation of placental DNA methylation in obese women exposed to Metformin during pregnancy
Maternal obesity in pregnancy is associated with increased birth-weight, obesity and premature mortality in adult offspring. The Effect of Metformin on Maternal and Fetal Outcomes in Pregnant Obese Women (EMPOWaR) trial was a randomised, double-blind, placebo-controlled trial carried out to determin...
ORGANISM(S): Homo sapiens 
2018-11-01 | E-MTAB-6421 | biostudies-arrayexpress
ProteomicsIntegrated omics analysis reveals metabolic adaptation of Clostridium thermocellum to lignocellulose-derived growth inhibitors released during the deconstruction of switchgrass
Integrated omics analysis reveals metabolic adaptation of Clostridium thermocellum to lignocellulose-derived growth inhibitors released during the deconstruction of switchgrass
ORGANISM(S): Hungateiclostridium Thermocellum (ncbitaxon:1515) 
MSV000080128 | MassIVE
TranscriptomicsCommon neuroinflammatory pathways in neurodegenerative diseases
Neurodegenerative diseases of the central nervous system are characterised by pathogenetic cellular and molecular changes in specific areas of the brain that lead to the dysfunction and/or loss of explicit neuronal populations. Despite exhibiting different clinical profiles and selective neuronal lo...
ORGANISM(S): Homo sapiens 
2011-01-29 | E-GEOD-26927 | biostudies-arrayexpress
UnknownLower vitamin D is associated with metabolic syndrome and insulin resistance in systemic lupus: data from an international inception cohort.
Not available
S-EPMC8487307 | biostudies-literature
UnknownLipoprotein(a) and Benefit of PCSK9 Inhibition in Patients With Nominally Controlled LDL Cholesterol.
Not available
S-EPMC8822604 | biostudies-literature
TranscriptomicsChromatin immunoprecipitation genome wide location analysis of yeast transcriptional regulators under multiple growth conditions
Genomic binding of 203 transcriptional regulatory proteins under various conditions. Hybridizations of fluorescently-labelled immunoprecipitated vs. whole-cell extract samples on S. cerevisiae intergenic arrays.
ORGANISM(S): Saccharomyces cerevisiae 
2004-09-02 | E-WMIT-10 | biostudies-arrayexpress
UnknownDonepezil delays progression to AD in MCI subjects with depressive symptoms.
Not available
S-EPMC2697965 | biostudies-literature
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